NCT07005921Befejeződött
QEEG-NEUROFEEDBACK FOR COGNITIVE REHABILITATION IN LONG COVID-19 SURVIVORS WITH BRAIN FOG
QEEG-NEUROFEEDBACK FOR COGNITIVE REHABILITATION IN LONG COVID-19 SURVIVORS WITH BRAIN FOG: A Sham-controlled, Double-blind, Randomized Controlled Trial
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. szept. 25.
Rövid összefoglaló (regiszter, angolul)
The pandemic has highlighted social, economic, educational, and political issues that have affected the health and quality of life of millions of Brazilians. Currently, attention and memory impairment remains predominant among the cognitive symptoms of Coronavirus observed in adults. The persistance of the reffered impairment after 12 weeks of COVID-19 is known as cognitive impairment in post-COVID-19 syndrome. Despite studies indicating the negative effects of COVID-19 on attention and memory, there is a gap in the literature regarding the investigation of QEEG-neurofeedback training (QEEG-NFT) efficacy for neurocognitive rehabilitation in COVID survivors with brain fog. In this context, quantitative electroencephalogram neurofeedback training (EEGq-NFT) is a promising non-invasive intervention designed to improve cognition, such as attention and working memory. By modifying electrophysiological patterns in the cerebral cortex. Considering the information presented, the question is what is the efficacy of EEGq-NFT training in rehabilitating attention and working memory in adults with cognitive impairment due to post-COVID-19 syndrome. This study aims to verify the efficacy of EEGq-NFT to rehabilitate cognition, more specifically attention, working memory and speed processing, in adults with cognitive impairment related to post-COVID-19 syndrome. A total of 40 participants were be randomly assigned to an EEGq neurofeedback training group (n = 13), an active control group called SHAM EEGq-neurofeedback (n = 13), and a waiting list control group (n = 14). The theta/beta ratio reduction protocol at frontal and central areas were used, with a total of 13 sessions. The Psychological Battery of Attention 2 (BPA-2), Digit Span Test (DST) and Five Digit Test (FDT) were employed to measure attention, working memory and speed processing levels. Statistical analyses were performed using JASP and R softwares with statistical significance set at p < 0.05 for a 95% confidence interval. The research followed all ethical standards for studies involving human subjects and was submitted for review and approval at the Research Ethics Committee.
- Állapot (regiszter)
- Befejeződött
- Vizsgálattípus
- Beavatkozással járó
- Résztvevők száma
- 40 (tényleges)
- Első benyújtás
- 2025. jún. 3.
- Kezdés
- 2025. jún. 10.
- Elsődleges befejezés
- 2026. aug. 14.
- Fő szponzor
- Jade Carvalho Da Silva
- Betegségek
- Long COVID és ME/CFS
- NCT-szám
- NCT07005921
Mit vállalsz
- Vizsgálat típusa: Beavatkozással járó
- Bevont résztvevők: 40
- 2025. jún. 10. és az elsődleges befejezés (2026. aug. 14.) között
- 1 helyszín, 1 országban
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
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- The inclusion criteria were: 1) Present a history of positive diagnosis of COVID, 2) Present post-COVID-19 syndrome, as defined by the United Kingdom's National Institute for Health and Care Excellence (NICE), 3) Present a score equal or lower than 26 on the Montreal Cognitive Assessment (MoCA), 4) Be over 18 years old and under 60 years old, 5) Not use psychoactive substances, such as methylphenidate, benzodiazepines and hypnotics, 6) Not have a history of neurological and/or psychiatric diseases prior to or subsequent COVID-19, 7) Authorize participation in the study through the informed consent form. The exclusion criteria were: 1) Present physical or cognitive repercussions resulting from other diagnoses prior to or subsequent to COVID-19, 2) Discontinue participation in the study, 3) Present a history of attention and memory impairment prior to the diagnosis of COVID-19.
Életkor a regiszterben: 18 év – 60 év · Nem: nők és férfiak · Egészséges önkénteseket is fogad
Helyszínek (1)
Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.
| Helyszín | Város | Ország | Helyszín állapota |
|---|---|---|---|
| Santos Dumont Institute | Macaíba | Brazília | Ismeretlen állapot |
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