Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

Korábbi kezelés

• Life-threatening or unstable medical, surgical, or psychiatric condition that prohibits participation (including current or past intent to harm oneself or others within the prior 12 months and not receiving treatment)
• Already prescribed the pilot medication at the time of study recruitment.

Más betegség

• Active engagement in formal alcohol treatment including medications for alcohol use disorder at the time of enrollment
• Untreated moderate to severe opioid use disorder
• History of serious hypersensitivity or adverse reaction to study medication
• Taking potentially interactive medication(s) for diabetes
• Diagnosis of type 1 Diabetes
• Personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, Severe gastrointestinal dysmotility, including gastroparesis, History of pancreatitis (does not pertain to patients for whom the cause of pancreatitis is known and no longer presents a risk), severe gallbladder disease

Laborértékek

• Self-report or laboratory test confirming pregnancy, nursing, or trying to conceive

Egyéb

• Residence out of state
• Inability to read or understand English
• BMI\<23
• Known Proliferative Diabetic Retinopathy, severe Non-Proliferative Diabetic Retinopathy, clinically significant Macular Edema, or Cystoid Macular Edema

• diagnosed with HIV
• Receive care at the Atlanta VA Healthcare System
• Age 18 or over
• Meet criteria for mild, moderate, or severe alcohol use disorder by the DSM-5 Alcohol Symptom Checklist and the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) screen
• Have evidence of significant alcohol use: PEth \> 20ng/ml
• Prescribed \>=5 medications
• Have cell phone or reliable contact number
• Can provide written informed consent