Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD

Korábbi kezelés

• Previous pancreatic surgery or total pancreatectomy.
• Severe comorbidities or American Society of Anesthesiologists (ASA) physical status classification IV or higher, making the patient unfit for surgery.
• Patients undergoing neoadjuvant chemotherapy or radiotherapy prior to surgery.

Más betegség

• Evidence of distant metastases or locally advanced unresectable disease on preoperative imaging or clinical evaluation (e.g., liver metastases, peritoneal carcinomatosis, involvement of major vessels beyond resectability).

Laborértékek

• Preoperative serum albumin less than 2.5 g/dL, indicating severe malnutrition.

Egyéb

• Chronic pancreatitis confirmed by clinical, radiological, or histological criteria that could confound pancreatic stiffness assessment.
• Pregnancy or lactation.
• Contraindications to EUS (e.g., esophageal obstruction)

• Adult patients aged 18 years or older.
• Patients scheduled for elective pancreaticoduodenectomy (PD) due to pancreatic head or periampullary disease, including but not limited to:
  • Pancreatic cancer (all stages eligible if resectable)
  • Periampullary cancer
  • Bile duct cancer
  • Duodenal cancer
• Patients deemed suitable for PD by the multidisciplinary pancreatic surgery team based on preoperative imaging and clinical evaluation.
• Adequate organ function and physiological reserve to undergo major abdominal surgery, as determined by clinical assessment and anesthesiology evaluation.
  • Ability to provide written informed consent and comply with study procedures.