Impact of Dietary Guidance and Probiotics in the Treatment of Endometriosis and Irritable Bowel Syndrome in Women

Korábbi kezelés

• Endometriosis requiring surgical treatment during the study period;
• Inability to use oral medication;

Más betegség

• Chronic, severe, or uncompensated clinical conditions, such as: malnutrition (BMI <18); insulin-dependent diabetes (types 1 or 2); uncontrolled hypertension; lung disease such as asthma or other chronic obstructive pulmonary disease; hematologic and liver diseases; advanced-stage chronic kidney disease (grades 3, 4, and 5); metabolic disorders; and immunosuppression;
• Clinical conditions of the gastrointestinal tract that cause IBS-like symptoms, such as: inflammatory bowel disease (Chron's disease, ulcerative colitis), microscopic colitis, celiac disease, and lactose intolerance;
• Severe eating disorders, such as: bulimia, anorexia nervosa, and binge-eating disorder;
• Chronic use of any medication with potential interaction with probiotics, the intestinal microbiota, or the natural progression of the disease in the last 6 months (such as probiotics, antibiotics, antifungals, antihistamines, digestive medications, or treatments for constipation or diarrhea);
• History of alcohol or drug dependence;
• Inability to cooperate with investigators due to cognitive impairment or mental state.

Egyéb

• Patients who already consume healthy foods or are on a restrictive diet more than four days a week, which may affect the evaluation results;
• Patients whose stool protopastological examination is altered;
• Pregnancy or lactation;
• Smoking in the last three years;

• Women between 18 and 50 years of age who wish to participate in the clinical trial;
• Willingness to voluntarily participate in the study and accept randomization to any of the three treatment arms;
• Participating exclusively in this clinical trial during the study period;
• Signing the Informed Consent Form (ICF) approved by the Research Ethics Committee (CEP) and CONEP