Effect of Early Neuromodulation Coupled With Rehabilitation on the Prevention of Post-stroke Pain

Korábbi kezelés

• Patients participating in another research protocol involving a drug in the 30 days prior to inclusion
• Drug or psychoactive substance abuse

Más betegség

• Contraindication to tDCS (epilepsy/history of epilepsy, intracranial ferromagnetic material or implanted stimulator, acute eczema or irritated skin over the stimulation area)
• Patients with Parkinson's disease
• Severe psychiatric disorders (e.g., schizophrenia)
• Any tumor disease with a life expectancy of <1 year

Egyéb

• Contraindication to MRI (use of a pacemaker or insulin pump, wearing of a metal prosthesis, intracerebral clip or piercing, claustrophobia)
• Cognitive or language difficulties preventing comprehension of instructions and/or correct clinical assessment
• Pregnant or breast-feeding women
• Patients under guardianship or curatorship, deprived of liberty, safeguard of justice
• Major depression
• The presence of pre-existing lesions >1.5 cm (maximum diameter) in a cerebral area belonging to the anatomically defined sensorimotor system
• Alcohol abuse
• Increased intracranial pressure
• Patients with a medical device containing electronics or conductive materials
• Patients on continuous oxygen (system not adapted)

• Age ≥18 years
• Ischemic or hemorrhagic stroke confirmed by MRI or scanner
• Lesion(s) in somato-sensory areas (i.e. mainly in: the pons, thalamus, internal capsule, basal ganglia and operculo-insular regions)
• Sensory and/or motor deficit requiring rehabilitation
• Subacute stage (7 to 45 days post-stroke)
• No neurological deficit or chronic neuropathic pain prior to stroke
• No neuropathic pain at inclusion
• Patient can be followed throughout the study.
• Information letter read and understood
• Able to give informed consent to participate in research
• Affiliation with a social security scheme