NCT07237529Toborzás még nem indult
What is the Feasibility of Narrative Exposure Therapy (NET) for People Experiencing Psychosis?
What is the Feasibility and Potential Impact of Narrative Exposure Therapy (NET) for People Experiencing Psychosis?
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. febr. 2.
Rövid összefoglaló (regiszter, angolul)
The goal of this interventional study is to evaluate the feasibility of Narrative Exposure Therapy (NET) for people experiencing psychosis. The secondary goal of this study is to evaluate the potential impact of NET in reducing symptoms of psychosis and post-traumatic stress. Participants will be patients accessing local NHS mental health services who are between the age of 18 to 65 years-old who have been diagnosed with a psychotic disorder and have a history of trauma. The main questions the study aims to answer are: Is NET feasible to deliver to people experiencing psychosis Can NET impact symptoms of psychosis in people experiencing psychosis? Can NET impact symptoms posttraumatic stress in people experiencing psychosis? Can NET impact symptoms of depression, anxiety and stress in people experiencing psychosis? Participants will be asked to: Undertake the NET intervention with a trained NET therapist (the number of sessions will be decided based on the need of the participant) Complete a questionnaire to assess the traumas they have experienced over the course of their life (called the 'Trauma and Life Events' Scale) Complete a weekly interview to assess their symptoms of psychosis (called the 'Simplified Negative and Positive Symptoms Interview') Complete weekly measures to assess symptoms of post-traumatic stress (called the 'International Trauma Questionnaire') Complete weekly measures to assess symptoms of depression, anxiety and stress (using the Depression, Anxiety and Stress 21 item Scale [DASS-21]) Complete a follow-up interview to discuss their personal experience of the NET intervention)
- Állapot (regiszter)
- Toborzás még nem indult
- Vizsgálattípus
- Beavatkozással járó
- Résztvevők száma
- 1 (tervezett)
- Első benyújtás
- 2025. szept. 19.
- Kezdés
- 2026. febr. 5.
- Elsődleges befejezés
- 2026. nov. 2.
- Fő szponzor
- University of Nottingham
- Betegségek
- Skizofrénia
- NCT-szám
- NCT07237529
Mit vállalsz
- Vizsgálat típusa: Beavatkozással járó
- Tervezett résztvevők: 1
- 2026. febr. 5. és az elsődleges befejezés (2026. nov. 2.) között
- Nincs megadott helyszín, ország nélkül
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.
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Korábbi kezelés
- Recent change in antipsychotic medication - If the person has recently started, stopped, or changed their antipsychotic medication. This is because there are no specific medical tests ("biomarkers") to predict how someone will respond to a new medication, and the effects can vary greatly between individuals. The first few weeks after a medication change can be a time of increased risk for worsening symptoms or relapse. Research also shows that stopping and starting medication can temporarily affect thinking skills such as memory and attention.
- Recent serious mental health crisis -
- If the person has experienced a significant adverse event within the last three months, such as:
- A hospital admission for mental health reasons This is because there is currently little research on how trauma-focused therapy affects people with severe mental illness who have recently been suicidal, and starting therapy too soon after a crisis may not be safe.
- Currently receiving another structured psychological therapy - For example, Cognitive Behavioural Therapy (CBT) or another regular talking therapy programme. This is to ensure that the results of the study reflect the effects of Narrative Exposure Therapy (NET) alone, without being influenced by another therapy.
Egyéb
- A suicide attempt
Kiket keres a vizsgálat
- Schizophrenia Spectrum and Other Psychotic Disorders
- Schizophrenia
- Schizoaffective Disorder
- Brief Psychotic Disorder
- Delusional Disorder
- Substance/Medication-Induced Psychotic Disorder
- Postpartum (Postnatal) Psychosis
- Individuals will be eligible to take part in the study if they meet all of the following:
- Age - between 18 and 65 years old.
- Language - able to speak and understand English well enough to take part in the research activities.
- Diagnosis - have a psychosis-related diagnosis as defined above.
- Trauma history - have experienced more than one traumatic event in their lifetime. A traumatic event means something that was deeply distressing, frightening, or life-threatening, such as abuse, assault, serious accident, disaster, or war.
- Current care - are under the care of a Local Mental Health Team (LMHT) within Nottinghamshire Healthcare NHS Foundation Trust and on the Care Programme Approach (CPA) pathway. CPA is an NHS care plan for people with complex mental health needs, setting out the support they will receive and who will provide it.
- Mobility - can travel independently to an NHS clinic or can be supported to attend.
- Consent - able to understand the study information and give informed consent to take part (in line with the Mental Capacity Act, 2005).
Életkor a regiszterben: 18 év – 65 év · Nem: nők és férfiak · Egészséges önkénteseket nem fogad
Ez az oldal tájékoztatás, nem orvosi tanács. Bármely vizsgálatról az orvosoddal beszélj.