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NCT07549828Toborzás még nem indult

Sebum Metabolomics and Lipidomics for Clinical Applications

Development of a Sample Collection Protocol and a Metabolomics/Lipidomics Analytical Strategy for Investigating Sebum and Its Clinical Applications

Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. ápr. 24.

Rövid összefoglaló (regiszter, angolul)

This study aims to develop a standardized workflow for sebum sampling and metabolomics/lipidomics analysis using Sebutape. A total of 200 participants will be recruited, including healthy individuals, patients with skin diseases, individuals undergoing dermatological treatments or using skincare products, and a subset of healthy participants receiving short-term topical antibiotic intervention. The study will investigate sebum composition, skin microbiome profiles, and their interactions under different conditions to explore potential biomarkers and clinical applications.

Állapot (regiszter)
Toborzás még nem indult
Vizsgálattípus
Beavatkozással járó
Résztvevők száma
200 (tervezett)
Első benyújtás
2026. ápr. 6.
Kezdés
2026. ápr. 1.
Elsődleges befejezés
2029. márc. 31.
Fő szponzor
National Taiwan University Hospital
NCT-szám
NCT07549828

Mit vállalsz

  • Vizsgálat típusa: Beavatkozással járó
  • Tervezett résztvevők: 200
  • 2026. ápr. 1. és az elsődleges befejezés (2029. márc. 31.) között
  • Nincs megadott helyszín, ország nélkül
  • Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket

A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.

Ki nem vehet részt

Szó szerint a(z) ClinicalTrials.gov forrásból, témák szerint csoportosítva. Hogy ki vehet részt, azt csak a vizsgálat csapata dönti el.

Korábbi kezelés

  • Use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
  • Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
  • Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
  • Participants Receiving Dermatological Treatments or Using Skincare Products
  • Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
  • Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.

Más betegség

  • Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
  • Presence of acute or chronic skin diseases, or chronic systemic diseases.
  • Any other conditions deemed unsuitable for participation by the principal investigator.
  • Participants with Skin Diseases or Specific Skin Conditions
  • Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
  • Severe disease that may compromise skin integrity or pose a risk to participant safety.
  • Any other conditions deemed unsuitable for participation by the principal investigator.
  • Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
  • Severe disease that may compromise skin integrity or pose a risk to participant safety.
  • Any other conditions deemed unsuitable for participation by the principal investigator.
  • Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
  • Known allergy or adverse reactions to the study intervention drug (topical antibiotic ointment containing bacitracin, polymyxin B, and neomycin).
  • Presence of visible skin disease, wounds, infection, inflammation, or other abnormal skin conditions at the sampling site.
  • Any other conditions deemed unsuitable for participation by the principal investigator.

Egyéb

  • Healthy Participants Undergoing Short-term Antibiotic Intervention

Kiket keres a vizsgálat

  • Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be in good health and suitable for participation.
  • No diagnosed skin diseases or chronic systemic diseases.
  • No use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
  • Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be suitable for participation.
  • Diagnosed by a physician or clinically assessed as having one of the following:
    • Acne
    • Atopic dermatitis
    • Seborrheic dermatitis
    • Psoriasis
    • Other common skin diseases
    • Specific skin conditions (e.g., postmenopausal or aging-related skin changes)
  • Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be suitable for participation.
  • Participants who, based on clinical needs or daily routines, are currently using or are expected to use or receive any of the following:
    • Physician-prescribed topical dermatological medications
    • Physician-prescribed systemic therapies (oral or injectable)
    • Routine use of general skincare products
    • Physician-directed non-invasive dermatological treatments
  • Individuals aged ≥20 years, regardless of sex or ethnicity.
  • Assessed by the investigator to be healthy, with skin condition suitable for the intervention used in this study.

A regiszterben nem jelölt feltételek

  • Healthy Participants

Életkor a regiszterben: 20 év – - · Nem: nők és férfiak · Egészséges önkénteseket is fogad

A teljes feltétellista: ClinicalTrials.gov

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