NCT07549828Toborzás még nem indult
Sebum Metabolomics and Lipidomics for Clinical Applications
Development of a Sample Collection Protocol and a Metabolomics/Lipidomics Analytical Strategy for Investigating Sebum and Its Clinical Applications
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. ápr. 24.
Rövid összefoglaló (regiszter, angolul)
This study aims to develop a standardized workflow for sebum sampling and metabolomics/lipidomics analysis using Sebutape. A total of 200 participants will be recruited, including healthy individuals, patients with skin diseases, individuals undergoing dermatological treatments or using skincare products, and a subset of healthy participants receiving short-term topical antibiotic intervention. The study will investigate sebum composition, skin microbiome profiles, and their interactions under different conditions to explore potential biomarkers and clinical applications.
- Állapot (regiszter)
- Toborzás még nem indult
- Vizsgálattípus
- Beavatkozással járó
- Résztvevők száma
- 200 (tervezett)
- Első benyújtás
- 2026. ápr. 6.
- Kezdés
- 2026. ápr. 1.
- Elsődleges befejezés
- 2029. márc. 31.
- Fő szponzor
- National Taiwan University Hospital
- Betegségek
- Atópiás dermatitisz (ekcéma), Pikkelysömör
- NCT-szám
- NCT07549828
Mit vállalsz
- Vizsgálat típusa: Beavatkozással járó
- Tervezett résztvevők: 200
- 2026. ápr. 1. és az elsődleges befejezés (2029. márc. 31.) között
- Nincs megadott helyszín, ország nélkül
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.
Ki nem vehet részt
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Korábbi kezelés
- Use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
- Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
- Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
- Participants Receiving Dermatological Treatments or Using Skincare Products
- Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
- Use of lotions, sunscreen, or other skincare products that may affect skin condition within 12 hours prior to sampling.
Más betegség
- Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
- Presence of acute or chronic skin diseases, or chronic systemic diseases.
- Any other conditions deemed unsuitable for participation by the principal investigator.
- Participants with Skin Diseases or Specific Skin Conditions
- Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
- Severe disease that may compromise skin integrity or pose a risk to participant safety.
- Any other conditions deemed unsuitable for participation by the principal investigator.
- Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
- Severe disease that may compromise skin integrity or pose a risk to participant safety.
- Any other conditions deemed unsuitable for participation by the principal investigator.
- Known allergy to Sebutape or similar adhesive tapes, or a history of related adverse reactions.
- Known allergy or adverse reactions to the study intervention drug (topical antibiotic ointment containing bacitracin, polymyxin B, and neomycin).
- Presence of visible skin disease, wounds, infection, inflammation, or other abnormal skin conditions at the sampling site.
- Any other conditions deemed unsuitable for participation by the principal investigator.
Egyéb
- Healthy Participants Undergoing Short-term Antibiotic Intervention
Kiket keres a vizsgálat
- Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be in good health and suitable for participation.
- No diagnosed skin diseases or chronic systemic diseases.
- No use of medications or receipt of dermatological treatments that may affect sebum secretion or the skin microbiome within the past two weeks.
- Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be suitable for participation.
- Diagnosed by a physician or clinically assessed as having one of the following:
- Acne
- Atopic dermatitis
- Seborrheic dermatitis
- Psoriasis
- Other common skin diseases
- Specific skin conditions (e.g., postmenopausal or aging-related skin changes)
- Individuals aged ≥20 years, regardless of sex or ethnicity, and assessed by the investigator to be suitable for participation.
- Participants who, based on clinical needs or daily routines, are currently using or are expected to use or receive any of the following:
- Physician-prescribed topical dermatological medications
- Physician-prescribed systemic therapies (oral or injectable)
- Routine use of general skincare products
- Physician-directed non-invasive dermatological treatments
- Individuals aged ≥20 years, regardless of sex or ethnicity.
- Assessed by the investigator to be healthy, with skin condition suitable for the intervention used in this study.
A regiszterben nem jelölt feltételek
- Healthy Participants
Életkor a regiszterben: 20 év – - · Nem: nők és férfiak · Egészséges önkénteseket is fogad
Ez az oldal tájékoztatás, nem orvosi tanács. Bármely vizsgálatról az orvosoddal beszélj.