AKK Study in Improving Obesity and Metabolic Status in Children and Adolescents

Korábbi kezelés

• Have used antibiotics, probiotics, prebiotics or synbiotic products within 3 months prior to screening.
• Have a history of systemic use of glucocorticoids or other drugs that may affect weight and metabolism (such as metformin, systemic glucocorticoids, diuretics, etc.) within 1 month prior to screening.

Más betegség

• Have a definite endocrine disorder causing obesity (such as Cushing's syndrome, hypothyroidism), a genetic syndrome (such as Prader-Willi syndrome), or other known organic diseases.
• Have a severe primary disease of the liver, kidney, cardiovascular system, respiratory system or hematopoietic system, etc.
• Subjects are allergic to any component of the study product (AKK probiotic capsules or placebo).
• Have a history of severe gastrointestinal diseases, such as inflammatory bowel disease (IBD).
• Other conditions as determined by the researcher to be unsuitable for participation in this study.

Egyéb

• Subjects are participating in other clinical trials.

• Age range: 7 years old to 18 years old (inclusive of boundary values), gender not restricted.
• Primary obesity: According to the WS/T 586-2018 standard issued by the National Health Commission of China, or the internationally recognized CDC/WHO standard, diagnosed as obesity (if BMI ≥ the 95th percentile of children of the same age and gender).
• The subjects and their legal guardians understand the research content, voluntarily participate and sign the written informed consent form (for guardians), and the informed consent form (for children aged 8 years and above).
• Able to comply with the research protocol, complete all visits and sample collection.