A Randomized, Double-blind, Placebo-controlled Study Evaluating the Effect of LAE102 Injection in Combination With Tirzepatide on Body in Obese Participants

Korábbi kezelés

• Previously underwent surgical or endoscopic weight loss metabolic surgery (except for local liposuction within 1 year before screening) or gastric balloon implantation, or planned to undergo any weight loss surgery or receive other weight loss treatments during the study;

Más betegség

• A clear diagnosis of type 1, type 2 diabetes or other types of diabetes (excluding gestational diabetes);
• Uncontrolled thyroid disease, or screening criteria.

Laborértékek

• Screening criteria: Glycated hemoglobin ≥ 6.5% or fasting blood glucose ≥ 7.0 mmol/L.
  • Obesity related:

Egyéb

• Diagnosed with secondary obesity;

• Voluntarily participate in the study and sign the Informed Consent Form (ICF);
• Male or female participants aged between 18 and 75 years (inclusive) at the time of signing the ICF;
• BMI ranging from 28.0 to 40.0 kg/m2 during the screening;
• Self-reporting at least one experience of weight loss failure after adjusting diet and exercise, and within the previous 3 months, the weight change after only dietary and exercise adjustments was less than 5%;