Toborzás még nem indultNo phase
Implementation of New Models of Ovarian Carcinoma Resistant to Therapy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mario Negri Institute for Pharmacological Research
- Trial code
- NCT07757711
- Record updated
- 2026. augusztus 11.
- Original description
The project focuses on developing new experimental models of ovarian cancer that accurately reflect patients who do not respond to first-line platinum-based treatments and who are resistant to PARP inhibitors (PARPi). These models are essential for testing new drugs or drug combinations in preclinical settings that closely mimic real clinical conditions. These models will also help to identify predictive biomarkers of treatment response and to better understand the biological mechanisms behind therapy resistance.Read full original descriptionShow less
The project focuses on developing new experimental models of ovarian cancer that accurately reflect patients who do not respond to first-line platinum-based treatments and who are resistant to PARP inhibitors (PARPi). These models are essential for testing new drugs or drug combinations in preclinical settings that closely mimic real clinical conditions. These models will also help to identify predictive biomarkers of treatment response and to better understand the biological mechanisms behind therapy resistance.
Inclusion: Female patients with malignant ovarian gynecological disease; Age 18 years or older; Patients capable of providing informed consent.
Exclusion: -Failure to sign the informed consent form.