Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity

Korábbi kezelés

• Having medical implants, such as a pacemaker or metal joint replacements, or other metal implants contraindicated for MRI
• Cosmetic implants, such as breast implants
• Prior amputation or major body-altering surgery that could invalidate body composition estimates

Más betegség

• Having claustrophobia or a history of claustrophobia
• Known HIV infection
• Known hydration abnormality (e.g., significant edema, end-stage renal disease, end-stage liver disease)
• Severe illness or life-threatening conditions such as end-stage kidney, liver, lung disease, NYHA III-IV heart failure, or active malignancy

Egyéb

• Being pregnant or attempting to become pregnant
• Having a height greater than DXA scanning limit (77 inches)
• Having a body weight greater than indicated for the equipment (400 lbs)
• Known Lipodystrophy

• Being willing to provide written informed consent prior to participation Being willing to complete the study visits and comply with the study procedures
• Being willing to travel to the various study locations for On-site, DXA, MRI, and Phlebotomy visits
• Being willing to change into appropriate form-fitting clothing for 3DO assessments and/or appropriate gowns for DXA and MRI imaging
• Must have a BMI within the range of 18.5 - 45 kg/m2
• Being willing to refrain from all food, drink, and substances for 8 hours prior to the On-site visit(s) and phlebotomy visit
• Being willing to refrain from all food, drink, and substances for 4 hours prior to the DXA and MRI scan visits
• Being willing to refrain from any exercise or vigorous physical activity for 24 hours prior to all visits
• Stable weight (no more than 5 kg change) for 3 months prior to screening
• If recruited in the Phoenix, AZ area, participants must be willing to drive yourself to the Phoenix Office location for the On-site Visits 1 and 2 (if applicable) located at the Exponent Phoenix Office.