Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer

Korábbi kezelés

• Presence of any other concurrent, actively treated malignancy

Más betegség

• Distant metastatic malignancy of any kind
• Any other condition that would, in the Investigator's judgment, contraindicate the patient's participation in the clinical study due to safety concerns with clinical study procedures

Egyéb

• Enrollment in any other program (e.g., weight loss program) that may alter the impact of exercise on outcomes
• Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including compliance issues related to feasibility/logistics)

• Documented informed consent of the participant and/or legally authorized representative
  • Assent, when appropriate, will be obtained per institutional guidelines
• Agreement to allow the use of archival tissue from diagnostic tumor biopsies
  • If unavailable, exceptions may be granted with study principal investigator (PI) approval
• Age: 40-80 years
• Body mass index (BMI): > 25 kg/m\^2
• Has Apple Health application (app) on personal device with valid iOS operating software (i.e., iOS 15.0 or higher)
• Has a registered MyChart/MyCityofHope account (or be willing to register for one) and the app downloaded onto personal device
• Ability to read and understand English to review MyChart/MyCityofHope on-screen instructions to sync and share Apple Health data, and for safety during exercise testing
• Previously diagnosed with localized prostate cancer
• Completed pelvic radiotherapy 12-20 months ago
• Presence of abnormalities (e.g., polyps, lesions) in the colon
• Assessed for exercise participation as per pre-screening clearance via the Physical Activity Readiness Questionnaire (PAR-Q+) (stage 2 only)
• Low physical activity, defined by < 5,000 steps/day over the last 12 months as per Apple Health data (stage 2 only)