Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission

Korábbi kezelés

• Planned surgery requiring hospitalization.
• Any surgery planned during the first 6 months of the study that requires hospitalization.

Más betegség

• Unstable cardiovascular or respiratory disease.
• Uncontrolled diagnosed psychiatric disorder.

Laborértékek

• Another identified cause of fatigue based on the first-line assessment performed in this context (complete blood count, liver function tests, CRP, blood electrolyte panel, serum creatinine, iron studies, folate, vitamin B12, TSH, fasting blood glucose).

Egyéb

• Patients already meeting the WHO physical activity recommendations before inclusion (IPAQ score ≥1500).
• Current pregnancy or pregnancy planned during the study period.
• Inability, for technical or other reasons, to connect to the Internet for telemonitoring and/or telerehabilitation.
• Refusal to participate.
• Persons under legal guardianship or deprived of liberty.
• Participant currently in an exclusion period for another clinical study.
• Participant who cannot be contacted in case of an emergency.

• Patients with inflammatory bowel disease (IBD) in clinical and biological remission (CRP/fecal calprotectin) for more than 6 months:
  • Remission according to PRO2 (Patient-Reported Outcome): liquid stool frequency ≤2/day and abdominal pain score ≤1 for Crohn's disease; stool frequency score ≤1 and rectal bleeding score = 0 for ulcerative colitis.
  • CRP <5 mg/L.
  • Fecal calprotectin <250 µg/g.
• Patients with significant fatigue (FACIT-F score ≤40) persisting for at least 3 months before inclusion, confirmed by two successive FACIT-F questionnaire assessments: the first at the screening visit (M-3), after obtaining informed consent, serving as the baseline value, and the second at the inclusion visit (M0), confirming persistence of fatigue for at least 3 months.
• Adults aged 18 years or older.
• Medical certificate confirming fitness to participate in physical activity. If the participant does not have a recent certificate dated within the previous 3 months, a specific consultation with the treating physician will be required. This consultation will be covered by the sponsor.