Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes

Korábbi kezelés

• Active nicotine or illegal drug use

Más betegség

• Diabetes-related hospitalization, including for diabetic ketoacidosis or severe hypoglycemia, within 12 months of screening
• Poorly controlled hypertension, defined as systolic blood pressure at least 140 mmHg or diastolic blood pressure at least 90 mmHg
• Taking diabetes medications other than insulin
• Significant organ system dysfunction, such as severe pulmonary, renal, hepatic, or cardiovascular disease
• Diagnosed neuropathic or psychiatric illness
• Per the POWERbreathe device user manual: history of spontaneous pneumothorax; a collapsed lung that has not fully healed; a pacemaker or medical implant containing magnets or electronics; any condition of the eardrum, such as a burst eardrum that has not fully healed

Laborértékek

• Diagnosed anemia or known hemoglobin less than 10 g/dL

Egyéb

• Structured exercise more than 150 minutes per week for the last 3 months
• Pregnant, lactating, or planning to become pregnant within the study period
• Unstable weight, defined as more than 5% change in the last 3 months
• Alcohol consumption totaling more than 10 standard drinks per week
• Unable to grant voluntary informed consent
• Unable or unwilling to follow the study protocol

• Age 18 to 35 years
• Type 1 diabetes diagnosed more than 1 year before screening
• Hemoglobin A1c (HbA1c) 10.0% or less within the last 3 months (may be measured at screening)- Body mass index 18 to 29.9 kg/m\^2
• Stable insulin delivery method for the past 30 days
• Ability to read all device instructions and insulin pump settings
• Estimated glomerular filtration rate at least 60 mL/min/1.73 m\^2 within the last 3 months (may be measured at screening)
• Use of an insulin pump or insulin delivery by multiple daily injections
• Attendance at 3 or more diabetes care visits over the past 12 months