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Assessment of Transnational Performance of the Universal Cardiac Surgical Risk Score Across International Sites

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Trial details

Who runs it
Union Health System
Trial code
NCT07920575
Record updated
2026. november 5.
Original description
ATLAS is a prospective, observational, multicenter cohort study of how accurately the Universal Cardiac Surgical Risk Score (UCSRS) predicts 30-day outcomes after adult cardiac surgery, compared head-to-head with two established models, STS-PROM and EuroSCORE II. Consecutive adult patients undergoing cardiac surgery are enrolled at each participating center over 12 months. All three scores are recorded for each patient. No score is returned to the treating team or influences clinical care. Discrimination and calibration of each score are assessed against 30-day major adverse cardiac and cerebrovascular events (MACCE). The model under evaluation, UCSRS version 3.2, was specified and calibrated against published registry mortality using simulated patients before enrollment. No simulated patient has an outcome, so no performance claim is made before this study.Read full original descriptionShow less

ATLAS is a prospective, observational, multicenter cohort study of how accurately the Universal Cardiac Surgical Risk Score (UCSRS) predicts 30-day outcomes after adult cardiac surgery, compared head-to-head with two established models, STS-PROM and EuroSCORE II. Consecutive adult patients undergoing cardiac surgery are enrolled at each participating center over 12 months. All three scores are recorded for each patient. No score is returned to the treating team or influences clinical care. Discrimination and calibration of each score are assessed against 30-day major adverse cardiac and cerebrovascular events (MACCE). The model under evaluation, UCSRS version 3.2, was specified and calibrated against published registry mortality using simulated patients before enrollment. No simulated patient has an outcome, so no performance claim is made before this study.

Inclusion: Age 18 years or older; Undergoing cardiac surgery at a participating institution during its enrollment period (isolated CABG, isolated valve, combined CABG and valve, multiple valve, aortic surgery, redo sternotomy, or other adult cardiac surgical procedures, on- or off-pump); Enrolled consecutively, without selection.

Exclusion: Congenital heart surgery performed under a pediatric program; Heart transplantation or ventricular assist device implantation as the primary procedure; Age under 18 years; Cases in which the comparator scores cannot be computed from available pre-operative data.

ClinicalTrials.gov NCT07920575

Építés alatt, nem éles – Assessment of Transnational Performance of the Universal Cardiac Surgical Risk Score Across International Sites (NCT07920575) – Frontlight Research