PM2.5 Exposure, Obesity, and Cardiovascular Health
Key facts
- Where
- East Lansing, Egyesült ÁllamokSee the site
Where in Egyesült Államok
- Michigan State UniversityEast Lansing, Egyesült ÁllamokTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Michigan State University
- Trial code
- NCT07924839
- Record updated
- 2026. november 9.
- Original description
Obesity and exposure to fine particulate matter (particles of aerodynamic diameter less than 2.5 µm, PM2.5) air pollution are established risk factors for cardiovascular (CV) morbidity and mortality. This proposed pilot project seeks to assess interactions between PM2.5 exposure, obesity, CV health, and dietary antioxidant in subjects with obesity.Read full original descriptionShow less
Investigating Interactions Between PM2.5 Exposure, Obesity, Cardiovascular Health and Dietary Antioxidant in Subjects With Obesity
Obesity and exposure to fine particulate matter (particles of aerodynamic diameter less than 2.5 µm, PM2.5) air pollution are established risk factors for cardiovascular (CV) morbidity and mortality. This proposed pilot project seeks to assess interactions between PM2.5 exposure, obesity, CV health, and dietary antioxidant in subjects with obesity.
Inclusion: ≥21 years old; diagnosis of hypertension (BP ≥140/90 mm Hg); obesity (BMI>30).
Exclusion: cancer receiving active treatment or chemotherapy; CV medication change in the prior month; any CV event (myocardial infarction, stroke, heart failure) in the past 3 months; unstable CV condition (class 3-4 angina or heart failure) or any medical condition that would place the subject at risk from participation or jeopardize study integrity (per investigators); lung disease requiring oxygen; expected overnight travel outside their home during the 9-week study period; unable to comprehend/sign informed consent; CPAP use for sleep apnea.