Decentralized, Status Neutral, Stakeholder-engaged, Post-incarceration Intervention for People Living With and at Risk for HIV
Key facts
- Where
- Long Island City és Philadelphia, Egyesült ÁllamokSee the 2 sites
Where in Egyesült Államok
- The Fortune SocietyLong Island City, Egyesült ÁllamokNo longer taking part
- Philadelphia FIGHTPhiladelphia, Egyesült ÁllamokNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Montefiore Medical Center
- Trial code
- NCT07927673
- Record updated
- 2026. november 10.
- Original description
One out of six people with HIV (PWH) in the U.S. are incarcerated annually; two-thirds of individuals who are incarcerated meet criteria for substance use disorder (SUD) and many more in carceral settings have risk factors for HIV. Ending the U.S. HIV epidemic hinges on linking and engaging people with criminal legal system involvement (PCLSI) with HIV or related risk factors, especially those with SUDs, to optimize antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) uptake and adherence.Read full original descriptionShow less
One out of six people with HIV (PWH) in the U.S. are incarcerated annually; two-thirds of individuals who are incarcerated meet criteria for substance use disorder (SUD) and many more in carceral settings have risk factors for HIV. Ending the U.S. HIV epidemic hinges on linking and engaging people with criminal legal system involvement (PCLSI) with HIV or related risk factors, especially those with SUDs, to optimize antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) uptake and adherence.
In this study, the investigator team will pursue Aim 1 (R33): Test the DEST2nation model in a multisite randomized control trial; and Aim 2 (R33): Estimate the cost of implementing and sustaining a decentralized, status neutral model and estimate its economic value from healthcare sector, state-policymaker, and societal perspectives.
Inclusion: Fortune or FIGHT client; Greater than or equal to 18 years old at time of informed consent; Living with HIV, or HIV-negative with risk factors for HIV and/or requests for PrEP; Current or history of substance use disorder; Fluent in English or Spanish; Resident of New York City (NYC) or Philadelphia County; Released from jail or prison system within the past 12 months.
Exclusion: Currently on PrEP; Unable to provide informed consent; Unable to complete study visits over 12 months; Does not plan to live in NYC or Philadelphia County for the next 12 months; Current suicidality determined by the Columbia-Suicide Severity Rating Scale (C-SSRS); Enrolled in PA-LINKS study (FIGHT participants); Participated in the DEST2nation pilot study (Fortune participants).