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Stem cell treatment & Frontotemporal dementia

Checked 11 Nov 2026 · Frontotemporal dementia

Written from the studies on PubMed, searched on 11 Nov 2026. Every number below comes from a study listed under Sources.

What people read

Posts online say that Stem cell treatment helps with Frontotemporal dementia.

What has been studied

  • 0In people
  • 0In animals
  • 12Only in the lab

What the studies found

Stem cell treatment has been studied for Frontotemporal dementia only in cells in the lab.

We found 21 published papers on Stem cell treatment and Frontotemporal dementia. They were published between 2015 and 2025.

0 of them are studies in people (0 randomised trials), 6 are reviews, 0 are studies in animals and 12 are studies only in the lab.

The most important ones are listed under Sources.

What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Induced pluripotent stem cell models as a tool to investigate and test fluid biomarkers in Alzheimer's disease and frontotemporal dementia.2024 · Brain Pathol · Review
  2. Human Induced Pluripotent Stem Cell Models of Frontotemporal Dementia With Tau Pathology.2021 · Front Cell Dev Biol · Review
  3. Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells.2020 · Mol Cell Neurosci · Review
  4. Concise Review: Modeling Neurodegenerative Diseases with Human Pluripotent Stem Cell-Derived Microglia.2019 · Stem Cells · Review
  5. Motoneuron Disease: Clinical.2017 · Adv Neurobiol · Review
  6. Review: Induced pluripotent stem cell models of frontotemporal dementia.2016 · Neuropathol Appl Neurobiol · Review
  7. Generation of Induced Pluripotent Stem Cells and Neuroepithelial Stem Cells from a Family with the Pathogenic Variant p.Q337X in Progranulin.2025 · Int J Mol Sci · In the lab
  8. Patient-derived induced pluripotent stem cells with a C9orf72 expansion as a model to study frontotemporal dementia pathologies.2025 · Mol Biol Cell · In the lab
  9. Sporadic ALS induced pluripotent stem cell derived neurons reveal hallmarks of TDP-43 loss of function.2025 · Nat Commun · In the lab
  10. Cell autonomous microglia defects in a stem cell model of frontotemporal dementia.2024 · medRxiv · In the lab
  11. Editorial Note: Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau.2024 · PLoS One · Other paper
  12. Neural stem cell homeostasis is affected in cortical organoids carrying a mutation in Angiogenin.2024 · J Pathol · Other paper
  13. Generation of a human induced pluripotent stem cell line (INEUi001-A) from an amyotrophic lateral sclerosis/frontotemporal dementia patient with a C9ORF72 G4C2 genotype of <2 (GGGGCCG) and 10 repeats.2023 · Stem Cell Res · Other paper

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More checked claims

Under construction, not live – Stem cell treatment & Frontotemporal dementia – Frontlight Research