Written from the studies on PubMed, searched on 11 Nov 2026. Every number below comes from a study listed under Sources.
The claim
Posts online say that stem cell treatment helps with hypertrophic cardiomyopathy.
Where research stands
We found 59 published papers on stem cell treatment and hypertrophic cardiomyopathy. They were published between 1998 and 2026. None of them is a study in people. 1 was a study in animals, and 41 were only in cells in the lab. 4 papers are reviews that sum up other studies.
- 0In people
- 1In animals
- 41Only in the lab
What the studies found
We have not summed up these studies in words yet. The most important papers are listed under Sources.
Verdict
Stem cell treatment has been studied for hypertrophic cardiomyopathy in animals, not yet in people.
Unproven means: it was only tested in animals or cells, or there is too little or mixed data from people. How we rate claims
What this means for you: Results in animals or in cells often do not hold in people. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Modeling hypertrophic cardiomyopathy with human cardiomyocytes derived from induced pluripotent stem cells.2022 · Stem Cell Res Ther · Review
- Human-induced pluripotent stem cells for modelling metabolic perturbations and impaired bioenergetics underlying cardiomyopathies.2021 · Cardiovasc Res · Review
- Cardiomyopathy phenotypes in human-induced pluripotent stem cell-derived cardiomyocytes-a systematic review.2019 · Pflugers Arch · Review
- Untangling the Biology of Genetic Cardiomyopathies with Pluripotent Stem Cell Disease Models.2017 · Curr Cardiol Rep · Review
- Stem cell activation sustains hereditary hypertrophy in hamster cardiomyopathy.2005 · J Pathol · In animals
- Generation of a human induced pluripotent stem cell line (ZZUNEUi040-A) from a male patient with hypertrophic cardiomyopathy carrying a heterozygous TPM1 (c.644C > T) mutation.2026 · Stem Cell Res · In the lab
- Long-term mavacamten exposure reduces force and sarcomere density in a human induced pluripotent stem cell-derived model of hypertrophic cardiomyopathy.2026 · Cardiovasc Res · In the lab
- Generation of two induced pluripotent stem cell lines from female patients harboring MYH7 mutations with hypertrophic cardiomyopathy.2026 · Stem Cell Res · In the lab
- Generation of two induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYBPC3 mutations.2026 · Stem Cell Res · In the lab
- Generation of induced pluripotent stem cells from an individual with early onset and severe hypertrophic cardiomyopathy linked to MYBPC3: c.772G > A mutation.2024 · Hum Cell · Other paper
- Generation of induced pluripotent stem cell lines from two unrelated individuals with familial hypertrophic cardiomyopathy carrying MYBPC3 nonsense mutations.2024 · Stem Cell Res · Other paper
- Corrigendum to "Generation of human induced pluripotent stem cell lines derived from four patients with a pathogenic ALPK3 variant associated with adult-onset hypertrophic cardiomyopathy (HCM)" [Stem Cell Res. 73 (2023) 103233].2024 · Stem Cell Res · Other paper
- Enhanced myofilament calcium sensitivity aggravates abnormal calcium handling and diastolic dysfunction in patient-specific induced pluripotent stem cell-derived cardiomyocytes with MYH7 mutation.2024 · Cell Calcium · Other paper
