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Stem cell treatment & Neuromyelitis optica (NMOSD)

Checked 11 Nov 2026 · Neuromyelitis optica (NMOSD)

Written from the studies on PubMed, searched on 11 Nov 2026. Every number below comes from a study listed under Sources.

What people read

Posts online say that Stem cell treatment helps with Neuromyelitis optica (NMOSD).

What has been studied

  • 2In people1 randomised trial
  • 2In animals
  • 2Only in the lab

What the studies found

Stem cell treatment has been tested in randomised trials in people with Neuromyelitis optica (NMOSD).

We found 36 published papers on Stem cell treatment and Neuromyelitis optica (NMOSD). They were published between 2010 and 2026.

2 of them are studies in people (1 randomised trials), 11 are reviews, 2 are studies in animals and 2 are studies only in the lab.

The most important ones are listed under Sources.

What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.

Sources

  1. Human Umbilical Cord Mesenchymal Stem Cells to Treat Neuromyelitis Optica Spectrum Disorder (hUC-MSC-NMOSD): A Study Protocol for a Prospective, Multicenter, Randomized, Placebo-Controlled Clinical Trial.2022 · Front Neurol · Randomised trial
  2. Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population.2011 · Ann Hematol · Study in people
  3. Controversies in neuroimmunology: Multiple sclerosis and other demyelinating disorders.2026 · Biomedica · Review
  4. Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder - recommendations from ECTRIMS and the EBMT.2025 · Nat Rev Neurol · Review
  5. Autologous hematopoietic stem cell transplantation for pediatric autoimmune neurologic disorders.2024 · Handb Clin Neurol · Review
  6. Hematopoietic stem cell transplantation for neuromyelitis optica spectrum disorder. Can immune tolerance be reestablished?2024 · Handb Clin Neurol · Review
  7. Comment on: Autologous hematopoietic stem cell transplantation in neuromyelitis optica spectrum disorder: A systematic review and meta-analysis.2023 · J Clin Neurosci · Review
  8. Autologous hematopoietic stem cell transplantation in neuromyelitis optica spectrum disorder: A systematic review and meta-analysis.2022 · J Clin Neurosci · Review
  9. Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study.2025 · Stem Cell Res Ther · In animals
  10. CFHR1-Modified Neural Stem Cells Ameliorated Brain Injury in a Mouse Model of Neuromyelitis Optica Spectrum Disorders.2016 · J Immunol · In animals
  11. Study of the cytological features of bone marrow mesenchymal stem cells from patients with neuromyelitis optica.2019 · Int J Mol Med · In the lab
  12. Autologous mesenchymal stem cells applied on the pressure ulcers had produced a surprising outcome in a severe case of neuromyelitis optica.2015 · Neural Regen Res · In the lab
  13. Longitudinal assessment of sNfL and sGFAP in severe NMOSD treated with allogeneic stem cell transplantation.2026 · Front Immunol · Other paper
  14. Long-term remission of neuromyelitis optica with allogeneic hematopoietic stem cell transplant.2026 · Med · Other paper
  15. Neuromyelitis Optica Spectrum Disorder in a Pediatric Patient Following Haploidentical Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia.2026 · Blood Cell Ther · Other paper
  16. Late Relapse After Autologous Hematopoietic Stem Cell Transplantation in AQP4-IgG-Positive NMOSD.2025 · JAMA Netw Open · Other paper

Search PubMed yourself

More checked claims

Under construction, not live – Stem cell treatment & Neuromyelitis optica (NMOSD) – Frontlight Research