Exploring gut microbiome dysbiosis in vasculitis in adults: a systematic review.

What was studied

This review looked at gut microbiota in adults with vasculitis. Gut microbiota means the germs that live in the gut. The authors compared people with vasculitis with healthy people. They searched several databases for papers up to May 2025. They included 12 papers.

What they found

Most of the papers saw changes in the diversity and richness of gut microbiota. The makeup of the gut communities differed from that in healthy people. Some common groups of gut bacteria were often lower in patients. These are Bacteroidetes, Firmicutes and Proteobacteria. Each kind of vasculitis was covered by only a few papers.

What it means for patients

The authors say gut imbalance is present in people with vasculitis. They say lower diversity and fewer gut bacteria may play a role. This role may be in starting and worsening the disease.

Why it is not certain yet

Only 12 papers were included, and they covered many kinds of vasculitis. One paper each covered some of those kinds. The abstract says the exact paths are still largely unknown. The review was not registered. A review can only be as good as the studies in it.

Source

Exploring gut microbiome dysbiosis in vasculitis in adults: a systematic review.

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