What researchers published on Huntington's disease
735 papers, newest first.
Showing 160 of 735
Not labelled yetSuperpixel-ComBat multi-site harmonization of unpaired T1W MRI data in Huntington's disease.Neuroimage. Reports
ReviewMiro1 and mitochondrial dysfunction in Huntington's disease: Emerging mechanistic links and therapeutic perspectives.Mitochondrion
Not labelled yetQualitative insights from partners of individuals with Huntington's disease: the quality of life of an under-researched population.Orphanet journal of rare diseases
Not labelled yetPrimer site variations resulting in false-negative Huntington's disease testing.Journal of medical genetics
Not labelled yetIsozyme-Specific Inhibition of GSK-3 Reveals Distinct Cellular Responses in Huntington's Disease Fibroblasts.Journal of neurochemistry
Not labelled yetThe SorCS2-derived macrocycle TT-P34 drives neuroprotection in animal models of neurodegeneration.Acta neuropathologica communications
ReviewThe hepatic secretome-microglia axis in huntington's disease: Linking peripheral metabolic dysfunction to neuroinflammation and novel therapeutic opportunities.Metabolic brain disease
Not labelled yetIn vivo assessment of brain microstructure in patients with Huntington's disease using quantitative MRI.Journal of neurology
Not labelled yetNeuroD1-induced fate conversion partially restores GABAergic neuronal identity in Huntington's disease.Molecular therapy : the journal of the American Society of Gene Therapy
Not labelled yetForecasting and Dynamics of Huntington's disease: A Machine Learning approach for Fractional-Order Mathematical Model.Journal of advanced research
Not labelled yetThe Treatment of Psychiatric Symptoms in Huntington's Disease: A Systematic Review.Current neuropharmacology
Not labelled yetRhes as a Potential Modulator of PINK1/Parkin-Dependent Mitophagy in Huntington's Disease.Journal of integrative neuroscience
Not labelled yetThe postsynaptic scaffolding protein SAPAP3 shapes mitochondrial activity: the case of Huntington's disease.Cell death & disease
Not labelled yetCell-specific transcription dysregulation in human Huntington's disease-positive developing striatum.Brain : a journal of neurology
Not labelled yetBioinformatics Analysis to Reveal Potential Targets of Huntington's Disease.IET systems biology
Not labelled yetCSF Leukocytes Transiently Increase Before Onset of Huntington Disease in Association With a Stage-Specific CSF Cytokine/Chemokine Pattern.Neurology(R) neuroimmunology & neuroinflammation
Not labelled yetComputational modeling and preclinical evaluation support targeting somatic instability for Huntington's disease treatment.Nature communications
Not labelled yetSomatic DNA-repeat expansions initiate distinct yet analogous changes in Huntington's disease cortical and striatal neurons.Cell
Not labelled yetMultimodal spatial transcriptomics redefines cortical pathology in Huntington's disease.Cell
ReviewNeuroprotective roles of Klotho signaling in Huntington's disease: From molecular insights to clinical translation.IBRO neuroscience reports
Not labelled yetEarly Administration of Methylene Blue Attenuates Mitochondrial Dysfunction and Cognitive Deficits in a Model of Huntington's Disease.Biology
Not labelled yetShould Huntington's Disease Remains the First Genetic Consideration in Adults Presenting with Combined Chorea and Ataxia in Resource-Limited Settings?Movement disorders clinical practice
Not labelled yetQuantifying multidisciplinary collaboration in Huntington's disease before and after service redesign: a social network analysis.BMC health services research
Not labelled yetHD-DRUM Rhythmic Training in Huntington's Disease: Feasibility, Motor, and Brain Microstructural Pilot Signals.Movement disorders clinical practice
PreprintCerebrospinal Fluid Myeloperoxidase Is Associated With Putamen Volume Beyond Neurofilament Light in Huntington's Disease.medRxiv : the preprint server for health sciences
Randomised trialAntidopaminergic Medications and Clinical Outcomes in Huntington Disease: Evidence From the PROOF-HD Placebo-Controlled Trial.Neurology
In plain wordsRead moreRead the paper on PubMedNot labelled yetHealthcare trajectories diverge years before Huntington disease is recorded in claims: a nationwide French matched cohort study.Journal of neurology, neurosurgery, and psychiatry
Not labelled yetEmotion regulation difficulties are selectively associated with executive and behavioural apathy in Huntington's disease.Journal of neurology
Not labelled yetBeyond Clinical Outcomes: What Antidopaminergic Medications Teach Us About Causal Inference in Huntington Disease.Neurology
Not labelled yetProgenitor transcriptional alterations link fetal and adult pathology in Huntington's disease.Brain : a journal of neurology
ReviewBeyond inherited repeat length: somatic expansions in Huntington disease.Current opinion in genetics & development
Not labelled yetCas9 nickase-mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington's disease mouse model.Science translational medicine
ReviewThe potential of AI inspired approaches for patient monitoring in drug development for Huntington's disease: capturing the digital exhaust for activities of daily living.Frontiers in molecular medicine
Not labelled yetAutonomic dysfunction in patients with Huntington's disease: Evidence from standardized cardiovascular reflex testing.Journal of Huntington's disease
Not labelled yetHuntington's disease clinical trials update: August 2026.Journal of Huntington's disease
ReviewNeuroprotective Role of Withaferin A in Huntington's Disease: Current Evidence and Future Perspectives.Molecular neurobiology
Not labelled yetThe Power of Two: Combined MSH3/HTT Silencing in Huntington's Disease.Movement disorders : official journal of the Movement Disorder Society
Not labelled yetiPSC neurodegenerative disease initiative isogenic CAG repeat iPSC line for Huntington's disease.Journal of Huntington's disease
Not labelled yetAttentional emotional bias in Huntington's disease: The "Hyper-Positive" effect.Cognitive, affective & behavioral neuroscience
Not labelled yetNeurofilament Light Chain and Mutant Huntingtin Across Huntington's Disease Integrated Staging System Stages in Huntington Disease: A Cross-Sectional Multimodal Analysis.Movement disorders : official journal of the Movement Disorder Society
Not labelled yetRecent Advances in Pharmacological Interventions for Huntington's Disease: Evidence from Clinical Translation.Reviews on recent clinical trials
Not labelled yetHuntington's disease vasculopathy is barrier-type-selective and arteriolar-dominant with spatially-coupled astrogliosis and reversible by S1pr1 stimulation.Nature communications
Not labelled yetUnmasking Huntington Disease: How a Neuropsychiatric Crisis Overcame Cultural Barriers to a Delayed Diagnosis.Clinical case reports
Not labelled yetRole of Miro1 in Mitochondrial Dysfunction and Neurodegeneration in Huntington's Disease.Current neurovascular research
Case reportJuvenile Huntington Disease With Cerebellar-Predominant Atrophy Identified by Genome Sequencing.Annals of clinical and translational neurology
Not labelled yetStriatal astrocyte μ-crystallin (Crym) loss contributes to early-stage Huntington's disease pathophysiology.Neuron
Not labelled yetPlasma Lipid Remodeling across Preclinical Burden, Disease Onset, and Early Motor Severity in Huntington's Disease.Movement disorders : official journal of the Movement Disorder Society
PreprintEffect of Vesicular Monoamine Transporter Type-2 Inhibitors on Motor Features in HD.medRxiv : the preprint server for health sciences
Not labelled yetSafety and efficacy of SOM3355 in patients with Huntington's disease (SOMCT03): a phase 2b, randomised, placebo-controlled, multicentre, dose-ranging study.EClinicalMedicine
PreprintDepletion of border-associated macrophages impairs CSF flow and exacerbates extranuclear mutant Huntingtin aggregation in the zQ175DN mouse model of Huntington's disease.bioRxiv : the preprint server for biology
Not labelled yetPellagra encephalopathy in Huntington disease: An autopsy case.Journal of neuropathology and experimental neurology
Not labelled yetJoint Analysis for Multivariate Longitudinal and Event Time Data With a Change Point Anchored at Interval-Censored Event Time.Statistics in medicine
Not labelled yetStaging disease without illness: ethical issues of the Huntington's Disease Integrated Staging System (HD-ISS).Journal of medical ethics
ReviewMonitoring huntingtin aggregation in Huntington's disease: methods, challenges and future opportunities.Expert review of proteomics
ReviewExtracellular Vesicles and Exosomes as Biomarkers in Huntington's Disease: Uncovering Pathogenic Insights and Pioneering Therapies.Molecular neurobiology
ReviewHope or hype: novel disease-modifying treatments for Huntington disease.Parkinsonism & related disorders
Not labelled yetNationwide survey and epidemiology of Huntington's disease in Hungary.Neuroepidemiology
Not labelled yetLycium barbarum glycopeptide alleviates the neuropathology in Huntington's disease mouse models.Neural regeneration research
ReviewChaperone-mediated remodelling of mutant huntingtin.Philosophical transactions of the Royal Society of London. Series B, Biological sciences
ReviewMechanistic Differences in Adult-Onset and Juvenile-Onset Huntington's Disease and the Potential Role of Neurodevelopment.Cureus
PreprintRestoring Aquaporin-4 alleviates molecular and motor phenotypes in zQ175 mouse model of Huntington's disease.bioRxiv : the preprint server for biology
PreprintComputer vision-aided locomotor behavioral analysis identifies therapeutic motor signatures in a mouse model of Huntington's disease.bioRxiv : the preprint server for biology
Not labelled yetAgentic AI for Clinical Outcomes Research, Population Health Management Analyses With Large Administrative Databases, and Generating Epidemiological Estimates of Diseases: Feasibility and Validation Study.Journal of medical Internet research
ReviewZebrafish as an Alternative Animal Model of Huntington's Disease: Challenges and Future Directions.Journal of integrative neuroscience
Not labelled yetDevelopment of Antisense Gapmers for the Treatment of Huntington's Disease.Methods in molecular biology (Clifton, N.J.)
Not labelled yetSex-dependent mild cardiac dysfunction and neurometabolic abnormalities in a model of Huntington's disease.Disease models & mechanisms
ReviewEstrogen and progesterone receptor signaling as candidate neuroendocrine modulators in Huntington's disease.Neurodegenerative disease management
Not labelled yetMasking phosphatidylserine prevents neuronal loss in two distinct Drosophila models of neurodegeneration.Proceedings of the National Academy of Sciences of the United States of America
Not labelled yetExpression of mutant Huntingtin induces proteasomal defects, mitochondrial abnormalities, and cell death in Drosophila muscles.Biochemical and biophysical research communications
ReviewPlanning advanced therapy trials for Huntington's disease: Ethical considerations.Molecular therapy : the journal of the American Society of Gene Therapy
Not labelled yetCorrection: Remote smartphone-based spoken language screening predicts clinical markers in Huntington's disease.Journal of neural transmission (Vienna, Austria : 1996)
ReviewUncovering hidden protein networks in Huntington's disease: implications for pathogenesis and therapy.Molecular biology reports
Not labelled yetExploring factors that influence meal management and eating behaviours in people living with Huntington's disease.Disability and rehabilitation
ReviewDefective membrane dynamics in Huntington's disease: A role of Rab11 dysfunction.Journal of Huntington's disease
Case reportChorea-predominant SCA5 mimicking Huntington's disease: A case report with a novel SPTBN2 variant.Clinical parkinsonism & related disorders
Not labelled yetmiR-196a reduces mutant Huntingtin aggregates by Rad23b-mediated degradation in Huntington's disease.Journal of biomedical science
ReviewFluid and Imaging Biomarkers in Huntington's Disease.Current neurology and neuroscience reports
ReviewImaging the glymphatic system in Huntington's disease: The benefits of a multimodal approach and clinical implications.International review of neurobiology
ReviewIndoleamine 2,3-dioxygenase 1 inhibitors: Molecular pharmacology, structural biology and medicinal chemistry with therapeutic perspectives for Huntington's disease.Biochimica et biophysica acta. Proteins and proteomics
Not labelled yetuniQure Submits U.S., U.K. Applications for Huntington's Disease Candidate.Human gene therapy
Not labelled yetEsketamine for treatment of depression in Huntington's disease: A case report.Journal of Huntington's disease
Not labelled yetMeal timing as medicine: clinical evidence for intermittent fasting in Huntington's disease.Nature metabolism
Trial resultEffects of time-restricted eating in early-stage Huntington's disease: a pilot study.Nature metabolism
In plain wordsRead moreRead the paper on PubMedNot labelled yetVisualizing Synaptic Disruptions in the Release and Regulation of Dopamine Hotspots in Huntington's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience
Not labelled yetAn Atlas of Modifiers of Age at Onset in Huntington's Disease.Current neuropharmacology
Not labelled yetLoss of interruption in the HTT CAG repeat is associated with somatic expansion and loss of medium spiny neurons in Huntington's disease.Neuron
Not labelled yetDecreased cerebrospinal fluid TNFRSF8 (sCD30) confirmed as a biomarker of Huntington's disease progression.Journal of neurology
Not labelled yetThe Trail Making Test in healthy controls and Huntington's disease: Demographic effects and normative tables based on a large data set.Psychological assessment
Not labelled yetEvaluation of curcumin as an exploratory pharmacological tool for modulating dysregulated molecular pathways in cellular models of Huntington's disease.Molecular biology reports
Not labelled yetNeuroimaging Findings in Three Patients with Juvenile Huntington's Disease.AJNR. American journal of neuroradiology
ReviewMicroRNAs in polyglutamine diseases: Mechanistic insights, circulating biomarkers, and emerging microRNA-based therapeutic strategies.Neurobiology of disease
Not labelled yetSesamum indicum-derived valdiate as a novel neuroprotective agent targeting PDE10A2 and SIRT1 in Huntington's disease.Frontiers in bioinformatics
Not labelled yetCombining Lycopene, Quercetin, and Poloxamer 188 Therapy Reduces Learning and Memory Deficits in the 3-nitropropionic Acid-induced Rat Model of Huntington's Disease.CNS & neurological disorders drug targets
Not labelled yetIdentification of Age-Associated Upstream Regulators to Promote Neuronal Resilience in HD Patient-Derived Neurons.Neuroscience bulletin
Not labelled yetTargeting Klotho Signaling for Neuroprotection in Huntington's Disease: A Comprehensive Review.Current molecular medicine
Not labelled yetNanotechnological and in vivo characterization of a new generation of brain-permeable nanoparticles for brain-targeted cholesterol delivery in Huntington's disease.International journal of pharmaceutics
Not labelled yetMapping brain volume changes in the zQ175DN mouse model of Huntington's disease: a longitudinal MRI study.Biomarker research
Not labelled yetPsychological interventions for individuals affected by Huntington's disease: effects on depression, anxiety, and emotional well-being.Journal of community genetics
Not labelled yetCross-species single-cell atlas of the striatum defines cell-type and subregion disease vulnerabilities.Cell
Not labelled yetMultimodal Characterization of Glymphatic-Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi-Cohort Retrospective Study.Annals of neurology
Not labelled yetUnawareness of motor deficit in Huntington's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Not labelled yetHuman-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7.Nature communications
Not labelled yetL-theanine from Camellia sinensis (L.) attenuates 3-NP-induced Huntington's disease-like alterations by remedying behavioral patterns and modulating neurotransmitters across three distinct brain regions: evidence from in-vivo and in-silico approaches.Metabolic brain disease
Not labelled yetA Cost-Effectiveness Analysis for Treatments of Patients with Early Stage Huntington's Disease in the USA.PharmacoEconomics - open
Case reportEarly Manifestations, Diagnostic Pathways, and Epilepsy in Juvenile-Onset Huntington Disease: A Three-Patient Case Series and Systematic Review.Brain sciences
Not labelled yetEarly reduction of myelin-associated glycoprotein at myelin membranes in Huntington's disease.Experimental neurology
ReviewRevealing the Mechanisms of Alzheimer's, Parkinson's and Huntington's Diseases Through Invertebrate Models.Biology
Not labelled yetGeometric properties of caudate and putamen mark the progression of Huntington's disease.Imaging neuroscience (Cambridge, Mass.)
ReviewThe pathophysiology of depression in Huntington's disease.Neuroscience and biobehavioral reviews
Not labelled yetDecoding neuronal vulnerability: Multidimensional analysis of D1R- and D2R- medium-sized spiny neurons in Huntington's disease.Brain pathology (Zurich, Switzerland)
ReviewUnraveling Neurodegeneration: Common Molecular Mechanisms and Novel Therapeutic Concepts in Major Neurodegenerative Disorders.Brain and behavior
Not labelled yetA porcine spectral assay library to quantify brain proteome by DIA-MS.Scientific data
Not labelled yetNetwork-based stratification of allele-specific expression reveals patient subgroups in Huntington's disease.Bioinformatics (Oxford, England)
ReviewHuntingtin, signaling endosomes and neuronal survival in health and Huntington disease.Journal of Huntington's disease
ReviewDysfunction of Primary Cilium in Huntington's Disease: How Mutant Huntingtin Disrupts This Cellular Signaling Hub.Biochemistry. Biokhimiia
Systematic reviewThe Role of MicroRNA in Diagnosis of Huntington's Disease: A Systematic Review.Molecular neurobiology
In plain wordsRead moreRead the paper on PubMedNot labelled yetIndicators of need and timing of percutaneous endoscopic gastrostomy (PEG) in people with Huntington's disease: A medical chart review study.Journal of Huntington's disease
PreprintTargeted quantification assays for DNA repair and handling proteins and interactions in Huntington's disease models.bioRxiv : the preprint server for biology
Not labelled yetIntracerebroventricular Administration of Gangliosides for In Vivo Functional Studies in Mice.Methods in molecular biology (Clifton, N.J.)
ReviewThe potential of vitamins in Huntington's disease: bridging mechanistic evidence with translational limitations and future strategies.Metabolic brain disease
Not labelled yetThe Role of PolyQ in Global Conformational Dynamics and Stability of Huntingtin.ACS chemical neuroscience
ReviewCurrent landscape and future perspectives of small-molecule therapeutics for Huntington's disease: From rational design to clinical translation.European journal of medicinal chemistry
Not labelled yetMultimodal balance training with rhythmical auditory cueing in Huntington's disease: A pilot randomized controlled trial.Journal of Huntington's disease
Not labelled yetDissociable Effects of Dysarthria Etiology and Severity on the Minimally Detectable Change of Speech Intelligibility.Journal of speech, language, and hearing research : JSLHR
Observational studyCSF Leukocytes Transiently Increase Before Onset of Huntington Disease in Association With a Stage-Specific CSF Cytokine/Chemokine Pattern.Neurology(R) neuroimmunology & neuroinflammation
ReviewMitochondrial dynamics in Huntington's disease.Journal of Huntington's disease
Not labelled yetReal-world treatment patterns and outcomes of deutetrabenazine in patients with chorea associated with Huntington disease: A retrospective chart review study.Journal of Huntington's disease
ReviewAlternative splicing dysregulation in CAG repeat expansion diseases.Trends in neurosciences
Not labelled yetCholesterol restores corticostriatal synaptic connectivity in Huntington's disease through BDNF/TrkB signalling, supporting a role for cholesterol pathways implicated by human genetic modifier studies.Pharmacological research
Not labelled yetBlocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington's disease pathogenesis in mice.Science translational medicine
Not labelled yetMissed Opportunities for Goals-of-Care Conversations in a Patient With End-Stage Juvenile Huntington's Disease: A Case Report.The American journal of hospice & palliative care
Not labelled yetIn vivo mapping of striatal neurodegeneration in Huntington's disease with Soma and Neurite Density Imaging.eLife
Not labelled yetEmerging Pharmacological Therapies for Huntington's Disease: Translational Insights from Recent Clinical Trials.Current pharmaceutical biotechnology
Not labelled yetAn automated speech measure for Huntington's disease: how can it take the field forward?The Lancet. Digital health
Not labelled yetEarly Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset.Movement disorders : official journal of the Movement Disorder Society
Not labelled yetGelatin methacryloyl hydrogel as a potential scaffold for cell transplantation for Huntington's disease.Brain communications
Not labelled yetWild-type C9orf72 drives proteasomal dysfunction and mutant aggregates via a Stat1-Isg15 axis in Huntington's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Not labelled yetJuvenile-onset Huntington's disease: a challenging diagnosis.Practical neurology
Not labelled yetGut microbiome composition in Huntington's disease: Stage-dependent differences between premanifest and manifest patients.Life sciences
Not labelled yetCholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington's disease.Translational neurodegeneration
ReviewMolecular insights of peroxisome proliferator-activated receptor-γ signalling in amyotrophic lateral sclerosis and Huntington's disease.International review of neurobiology
Not labelled yetAltered myelin sphingolipid and glycerophospholipid profiles in Huntington disease.Journal of Huntington's disease
ReviewWhat can clinical disorders involving the basal ganglia tell us about the pathophysiology of obsessive and compulsive symptoms?Journal of neural transmission (Vienna, Austria : 1996)
Not labelled yetEnhancing the detection of HTT1a with neoepitope antibodies in mouse models of Huntington's disease.Brain communications
Not labelled yetFalls in Huntington's Disease: A Cross-Sectional Analysis of Clinical Features and Potential Contributors.Movement disorders clinical practice
Not labelled yetAccelerated prefrontal intermittent theta-burst stimulation in Huntington's disease: a within-subject study of domain-specific behavioral and event-related potential changes.Frontiers in human neuroscience
Not labelled yetRevisiting the Link Between Huntington's Disease and Cancer: Evidence from the Enroll-HD dataset.Neuroepidemiology
Not labelled yetIn vivo CRISPR base editing for treatment of Huntington's disease.Nature biomedical engineering
Not labelled yetPsychosis in Huntington's disease: A case supporting multidisciplinary and early palliative care.Journal of Huntington's disease
Not labelled yetHDDF2-A Novel Patient-Derived Fibroblast Line from Huntington's Disease with Prominent Cellular Senescence and polyQ Pathology.Biomedicines
ReviewGrape Seed Extract as an Adjuvant Therapy for Huntington Disease; A Narrative Review of Biological Plausibility and Potential Clinical Outcomes.Molecules (Basel, Switzerland)
Not labelled yetPrevention of appearance of severe Huntington's disease symptoms in the R6/1 mouse model by early administration of 4',5,7-trihydroxyisoflavone.Journal of Huntington's disease
Not labelled yetIL17A disrupts autophagy-lysosomal function and lysosome reformation through the GSK3B-TFE3 signaling pathway in Huntington disease.Autophagy
Not labelled yetA novel machine learning approach for the classification of Huntington disease manifestation using motor features.Parkinsonism & related disorders
Not labelled yetA deep learning model for speech-based prediction of clinical scores in people with Huntington's disease: a longitudinal study with cross-sectional replication.The Lancet. Digital health
Not labelled yetDo young carriers of Huntington's disease mature earlier?Journal of Huntington's disease
ReviewMachine learning applications in Huntington's disease prognosis: A review.Journal of Huntington's disease
Not labelled yetRelationship Between miRNA and Neurodegenerative Diseases Such as Alzheimer's disease, Parkinson's, Huntington's disease, Amyotrophic Lateral Sclerosis.Mini reviews in medicinal chemistry
Not labelled yetUSP28 Deficiency is Linked to Impaired Ubiquitin-dependent Proteostasis in Huntington's Disease.Molecular neurobiology
ReviewFrom glycemic control to neuroprotection: alogliptin as a repurposed candidate for Huntington's disease.Metabolic brain disease