Down syndrome: who works on it

One card per institution. Pick a target or a country to narrow the list.

• All targets
• MAPT 0
• APP 0
• APOE 0
• BDNF 0
• JAK 1
• ACE2 0
• G6PD 0
• mTOR 0
• PD-1 1
• TNF 0

10 of 10+ institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• European Commission (Horizon Europe) · HORIZON-EIC-ACC

  FRAgile X syndrome Clinical trial: Unravelling the science behind this Rare disease in Europe (FRAXCURE)

  Connecta Therapeutics Sl· Barcelona, Spain· EU contribution €2,499,999· until Jun 2027

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  Aneuploidy and Its Impact on Blood Development: Context Matters (CONTEXT)

  Kobenhavns Universitet· Kobenhavn, Denmark· EU contribution €1,999,995· until Sept 2028

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon 2020) · RIA

  Improving COgnition in Down syndrome (ICOD)

  Consorcio Mar Parc de Salut de Barcelona· Barcelona, Spain· EU contribution €5,989,840· until Jul 2027· 3 countries

3 of 3 running projects, newest first. Listed amounts together: €10.5m.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Trials whose registry record says individual participant data (IPD) will be shared.

• A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

  NCT04546399· National Cancer Institute (NCI)· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 7
• Organoids 3
• CRISPR-Cas Systems 1
• Gene Expression Profiling 10
• Whole Genome Sequencing 1
• Exome Sequencing 5
• Proteomics 7
• Metabolomics 2
• Mass Spectrometry 1
• Flow Cytometry 5
• Immunohistochemistry 2
• Positron-Emission Tomography 8
• Magnetic Resonance Imaging 11
• Machine Learning 1
• Deep Learning 2
• Cohort Studies 25
• Genome-Wide Association Study 1

• Diagnostic yield of cancer predisposition in a nationwide prospective childhood acute leukemia cohort.

  Nat Commun, Sept 2026

  Ann Nordgren

See which targets of this disease your abstract mentions, and go to the people working on them.