Heart failure: who works on it

One card per institution. Pick a target or a country to narrow the list.

• All targets
• SGLT2 29
• GLP-1 6
• TTR 10
• AMPK 0
• NLRP3 0
• NRF2 0
• PI3K 0
• PPAR 0
• AKT 0
• mTOR 0
• HER2 2
• STAT3 0
• TP53 0
• MAPK 0
• SIRT1 0
• STING 0
• EGFR 0
• GIP 4
• HIF-1 0
• PCSK9 0
• DPP-4 0
• VEGF 0
• HMGB1 0
• IL-6 0
• TNF 0
• CTNNB1 0
• YAP 0
• PINK1 0
• ERK 0
• GPX4 0
• JAK 0
• TLR4 0
• IL-1 0
• JNK 0
• MEK 1
• HSP90 0
• DMD 0
• IL-17 0
• MMP-9 0
• PD-1 0
• CD40 0
• COX-2 0
• HDAC 0
• PD-L1 0
• TFEB 0
• ABL1 0
• APOE 0
• AR 0
• BCL-2 0
• FTO 0
• METTL3 0
• MYC 0
• PTEN 0
• ACE2 0
• BDNF 0
• BRAF 0
• BRD4 0
• BTK 0
• CDK4/6 0
• FAK 0

2 of 2+ institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Integrative Modeling of Autonomic dysfunction and Cardiac arrhyThmogenesis (IMpACT)

  Politecnico di Milano· Milano, Italy· EU contribution €193,643· until Aug 2029· 3 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  Bioinspired Modulation of Cardiac Troponin I Splicing to Treat Diastolic Dysfunction (TROPOSplice)

  Centro Nacional de Investigaciones Cardiovasculares Carlos Iii (F.s.p.)· Madrid, Spain· EU contribution €1,499,625· until Jan 2032

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC

  From n=1 to many: Scaling-up gene editing for future heart therapies (ONE2MANY)

  Klinikum Der Technischen Universität München (Tum Klinikum)· Muenchen, Germany· EU contribution €1,499,468· until Dec 2031

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  A computational framework for personalising atrial fibrillation treatment to minimise heart failure risk (AFHF-TAILOR)

  Eidgenoessische Technische Hochschule Zuerich· Zuerich, Switzerland· EU contribution €292,119· until Dec 2028· 2 countries

• European Commission (Horizon Europe) · HORIZON-CSA

  RAPid TranslatiOnal Research - Heart Failure (RAPTOR-HF)

  Uniwersytet Medyczny Im Piastow Slaskich We Wroclawiu· Wroclaw, Poland· EU contribution €15,000,000· until Dec 2032· 3 countries

5 of 84 running projects, newest first. Listed amounts together: €318.2m.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Trials whose registry record says individual participant data (IPD) will be shared.

• Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF

  NCT07630454· Yunlong Wang· Source

• Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart Valves

  NCT07610174· Kafrelsheikh University· Source

• CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry

  NCT07567378· JULIO GRANADOS MONTIEL· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 17
• Organoids 5
• Mendelian Randomization Analysis 79
• CRISPR-Cas Systems 7
• Gene Expression Profiling 71
• Sequence Analysis, RNA 1
• Whole Genome Sequencing 2
• Exome Sequencing 10
• Proteomics 108
• Metabolomics 64
• Mass Spectrometry 5
• Flow Cytometry 10
• Immunohistochemistry 13
• Xenograft Model Antitumor Assays 2
• Positron-Emission Tomography 37
• Magnetic Resonance Imaging 155
• Machine Learning 198
• Deep Learning 42
• Cohort Studies 501
• Genome-Wide Association Study 74

• Association of Risk-Stratified WeChat-Based Tele-Nursing With Self-Care Outcomes and Short-Term Readmission Among Patients With Chronic Heart Failure: A Retrospective Cohort Study.

  Nurs Health Sci, Dec 2026

• Association between triglyceride-glucose body mass index and future risk of arthritis in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: A national prospective cohort study.

  Medicine (Baltimore), Nov 2026

• Importance of Angina Pectoris by Coronary Artery Disease Severity.

  JAMA Netw Open, Nov 2026

• Explainable Machine Learning for Predicting Incident Heart Failure from Routine Electronic Health Record Data.

  J Card Fail, Nov 2026

• Sex-related differences in outcome of tricuspid valve surgery in severe isolated secondary tricuspid regurgitation.

  Eur Heart J Cardiovasc Imaging, Oct 2026

• Prognostic value of cardiac magnetic resonance global T2 mapping in patients with takotsubo syndrome.

  Eur Heart J Cardiovasc Imaging, Oct 2026

• Incident transient ischemic attack and subsequent cardiovascular events and mortality in patients with newly diagnosed type 2 diabetes: a population-based cohort study.

  Front Endocrinol (Lausanne), Oct 2026

• Early Rhythm Control vs Usual Care After Acute Ischemic Stroke in Patients With Atrial Fibrillation.

  Neurology, Oct 2026

• Dataset-Agnostic Biological Age Calculator and Predictions of Mortality in NHANES (1999-2010), UK Biobank (2006-2010), and Dalian Heart Failure (2015-2023) Cohorts: Development and Validation Study.

  JMIR Form Res, Oct 2026

• Contemporary outcomes after 100 consecutive HeartMate 3 LVAD implantations: a single-centre cohort study from a Swiss tertiary centre.

  Swiss Med Wkly, Oct 2026

See which targets of this disease your abstract mentions, and go to the people working on them.