Jun Yu

Now

Trials, publications and grants since Nov 2024.

• Publication

  Albumin-bound paclitaxel-induced stromal reprogramming drives resistance to neoadjuvant chemotherapy in patients with pancreatic cancer.

  Science translational medicine, Nov 2026

• Publication

  Sitagliptin, a repurposed diabetes drug, overcomes gemcitabine resistance in pancreatic cancer via ribonucleotide reductase inhibition: SITGEM-CARE phase 2 trial.

  Signal transduction and targeted therapy, Nov 2026

• Publication

  Senescent Cancer-Associated Fibroblasts Drive Early-Stage Lymph Node Metastasis in Pancreatic Cancer through Lactate-Mediated Metabolic-Epigenetic Rewiring.

  Cancer discovery, Aug 2026

• Publication

  Targeting GPR34 in damage-associated macrophages enhances anti-tumor immunity and the efficacy of Surufatinib in pancreatic cancer.

  Signal transduction and targeted therapy, Apr 2026

• Publication

  Rationally and in silico guided APOBEC3F-directed CBE for enhanced PDAC genetic therapy.

  Communications biology, Mar 2026

• Publication

  An Insulin-Exosome-TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer.

  Advanced science (Weinheim, Baden-Wurttemberg, Germany), Feb 2026

• Publication

  Pathomics Signature for Prognosis and CA19-9 Interception in Pancreatic Ductal Adenocarcinoma: A Real-Life, Multi-Center Study.

  Advanced science (Weinheim, Baden-Wurttemberg, Germany), Jan 2026

• Publication

  Targeting of the m6A eraser ALKBH5 suppresses stemness and chemoresistance of colorectal cancer.

  Nature communications, Dec 2025

• Publication

  Targeting TNK2/ACK1 reverses the immunosuppressive tumor microenvironment and synergizes with immunochemotherapy in pancreatic cancer.

  Nature communications, Dec 2025

Affiliations

• Tianjin Medical University Cancer Institute and Hospital

Co-authors

• CWChi Chun WongHow are we linked?
• CHChongbiao HuangHow are we linked?
• WKWei KangHow are we linked?
• XWXiuchao WangHow are we linked?

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