Moustafa Gabr

Targets

• COX-2 1
• TREM2 1

Filled chips are declared by the researcher; the others come from publications (number of works).

Now

Trials, publications and grants since Nov 2024.

• Publication

  AI-guided design of cyclic peptide binders targeting TREM2 using CycleRFdiffusion and experimental validation.

  Bioorganic & medicinal chemistry letters, Dec 2025

• Publication

  Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy.

  ACS omega, Dec 2025

• Publication

  Exploring pyrazolidinone and pyrazolidinedione scaffolds for Alzheimer's therapy: multitarget COX-2 inhibitors with anti-amyloid β, anti-tau, antioxidant, and neuroprotective activities.

  RSC medicinal chemistry, Nov 2025

• Publication

  Virtual Screening-Guided Discovery of Small-Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma Spheroids.

  ACS medicinal chemistry letters, Nov 2025

Affiliations

• Weill Cornell Medicine

Co-authors

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