Charlotte

The trials here

What the 7 trials at this site are about, from their registry records.

Conditions

• Amyloidosis2 trials
• Metastatic breast cancer2 trials
• Chronic kidney disease1 trial
• Epilepsy1 trial
• High blood pressure1 trial
• Myasthenia gravis1 trial

Phase

• Phase 32 trials
• Phase 1/21 trial
• Phase 21 trial
• Phase 41 trial

Status

• Recruiting4 trials
• Completed2 trials
• Active, not recruiting1 trial

Lead sponsor

• Alnylam Pharmaceuticals3 trials
• Alexion Pharmaceuticals, Inc.1 trial
• Arvinas Estrogen Receptor, Inc.1 trial
• Jazz Pharmaceuticals1 trial
• Olema Pharmaceuticals, Inc.1 trial

Running trials

• Recruiting

  DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

  NCT07358078· Alnylam Pharmaceuticals· Source

• Recruiting

  Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

  NCT07085767· Phase 3· Olema Pharmaceuticals, Inc.· Source

  Contact: Olema Pharmaceuticals, Inc.

• Recruiting

  TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

  NCT07052903· Phase 3· Alnylam Pharmaceuticals· Source

• Active, not recruiting

  Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution

  NCT05044819· Phase 4· Jazz Pharmaceuticals· Source

• Recruiting

  Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

  NCT04202341· Alexion Pharmaceuticals, Inc.· Source

  Contact: Alexion Pharmaceuticals, Inc. (Sponsor)

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Amyloidosis2 recruiting
• Metastatic breast cancer1 recruiting
• Myasthenia gravis1 recruiting

Closed trials

• Completed

  Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)

  NCT06272487· Phase 2· Alnylam Pharmaceuticals· Source

• Completed

  A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Participants With ER+/HER2- Locally Advanced or Metastatic Breast Cancer

  NCT04072952· Phase 1/2· Arvinas Estrogen Receptor, Inc.· Source