Manchester Royal Infirmary

The trials here

What the 38 trials at this site are about, from their registry records.

Conditions

• Acute myeloid leukaemia5 trials
• Multiple myeloma5 trials
• Childhood cancers4 trials
• Myelodysplastic syndromes4 trials
• Type 2 diabetes4 trials
• Chronic kidney disease3 trials
• Heart failure3 trials
• Lupus (SLE)3 trials
• Sickle cell disease3 trials
• Acute lymphoblastic leukaemia2 trials
• Aortic aneurysm2 trials
• Chronic lymphocytic leukaemia2 trials
• and 21 more

Phase

• Phase 312 trials
• Phase 28 trials
• Phase 2/32 trials
• Phase 11 trial
• Phase 1/21 trial

Status

• Completed14 trials
• Recruiting12 trials
• Active, not recruiting9 trials
• Not yet recruiting2 trials
• Terminated1 trial

Lead sponsor

• University of Birmingham3 trials
• Biogen2 trials
• Boehringer Ingelheim2 trials
• Imperial College London2 trials
• Janssen Research & Development, LLC2 trials
• and 25 more

Running trials

• Not yet recruiting

  Real-World Data Collection of GORE Devices Used In the Endovascular Treatment of Aortic Aneurysms Which Incorporate Visceral Arteries.

  NCT07480395· W.L.Gore & Associates· Source

• Recruiting

  A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis

  NCT07422532· Imperial College London· Source

  Contact: Hood Thabit, PhD

• Recruiting

  Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

  NCT07224360· Phase 2· CSL Behring· Source

  Contact: Trial Registration Coordinator

• Not yet recruiting

  The Practicality and Utility of Measured vs Estimated GFR in adCKD

  NCT07450534· Manchester University NHS Foundation Trust· Source

  Contact: Thomas Lindsay

• Recruiting

  Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

  NCT07053800· Phase 2· Autolus Limited· Source

  Contact: Autolus Ltd

• Recruiting

  EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  NCT07064473· Phase 3· Boehringer Ingelheim· Source

  Contact: Boehringer Ingelheim

• Recruiting

  Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  NCT07037459· Phase 3· Amgen· Source

• Recruiting

  A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

  NCT06609226· Phase 3· Novo Nordisk A/S· Source

  Contact: Novo Nordisk

• Active, not recruiting

  Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

  NCT06578247· Phase 3· Daiichi Sankyo· Source

• Active, not recruiting

  A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

  NCT06220201· Phase 1· Juno Therapeutics, Inc., a Bristol-Myers Squibb Company· Source

• Recruiting

  A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies

  NCT06045910· Phase 1/2· Cancer Research UK· Source

  Contact: Jane Norman, Dr

• Active, not recruiting

  Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure

  NCT05598333· Phase 2· AskBio Inc· Source

• Active, not recruiting

  CGM Use in Adults With Type 2 Diabetes on Basal Insulin

  NCT05944432· Abbott Diabetes Care· Source

• Recruiting

  Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer

  NCT05574647· Imperial College London· Source

  Contact: Charlene Hyde

• Active, not recruiting

  A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

  NCT05531565· Phase 2/3· Biogen· Source

• Active, not recruiting

  A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

  NCT04963296· Phase 3· Hoffmann-La Roche· Source

• Active, not recruiting

  A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

  NCT04923893· Phase 3· Janssen Research & Development, LLC· Source

• Recruiting

  Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

  NCT04774159· Phase 3· Population Health Research Institute· Source

  Contact: Tawqeer Rashid

• Recruiting

  Methods of T Cell Depletion Trial (MoTD)

  NCT04888741· Phase 2· University of Birmingham· Source

  Contact: MoTD Trial

• Active, not recruiting

  Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia

  NCT04579367· Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company· Source

• Active, not recruiting

  A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT

  NCT04217278· Phase 2/3· University of Birmingham· Source

• Recruiting

  Terumo Aortic Global Endovascular Registry

  NCT04246463· Vascutek Ltd.· Source

  Contact: David Murray, MR (principal investigator)

• Recruiting

  The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

  NCT03562169· Phase 3· University of Leeds· Source

  Contact: Alberto Rocci

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Aortic aneurysm2 recruiting
• Childhood cancers2 recruiting
• Chronic kidney disease2 recruiting
• Multiple myeloma2 recruiting
• Sickle cell disease2 recruiting
• Type 2 diabetes2 recruiting
• Acute lymphoblastic leukaemia1 recruiting
• Acute myeloid leukaemia1 recruiting
• Chronic lymphocytic leukaemia1 recruiting
• Chronic myeloid leukaemia1 recruiting
• Coronary artery disease1 recruiting
• Follicular lymphoma1 recruiting
• Heart failure1 recruiting
• High blood pressure1 recruiting
• Hodgkin lymphoma1 recruiting
• Lupus (SLE)1 recruiting
• Mantle cell lymphoma1 recruiting
• Myelodysplastic syndromes1 recruiting
• Myeloproliferative neoplasms1 recruiting
• Obesity1 recruiting
• Peripheral artery disease1 recruiting
• Prostate cancer1 recruiting
• Stroke1 recruiting
• Thalassaemia1 recruiting

Closed trials

• Completed

  A Study of Maribavir in Adults With Post-transplant Cytomegalovirus (CMV) Infection

  NCT06615921· Takeda· Source

• Completed

  Performance and Hearing-related Outcomes in Adults Implanted With the CI622D Dexamethasone-eluting Cochlear Implant Compared to Those Implanted With a Standard Cochlear Implant (CI622)

  NCT06424262· Cochlear· Source

• Completed

  A Real-world Study in Participants With Smoldering Multiple Myeloma

  NCT06472778· Janssen-Cilag Ltd.· Source

• Completed

  A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)

  NCT06077864· Phase 3· Boehringer Ingelheim· Source

• Completed

  Closing the Loop in People with Type 1 Diabetes

  NCT05653050· University of Cambridge· Source

• Completed

  Neuromuscular Stimulation Versus Intermittent Compression for Venous Thromboembolism Prophylaxis in Critical Care

  NCT05208216· Manchester University NHS Foundation Trust· Source

• Completed

  Research Study Investigating How Well NDec Works in People With Sickle Cell Disease

  NCT05405114· Phase 2· Novo Nordisk A/S· Source

• Completed

  Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3)

  NCT04880434· Phase 2· Kite, A Gilead Company· Source

• Completed

  Psychological Impact of COVID-19 on Intensive Care Survivors

  NCT05092529· Royal Liverpool University Hospital· Source

• Completed

  Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

  NCT04435626· Phase 3· Bayer· Source

• Terminated

  A Study to Evaluate Safety and Tolerability of Aducanumab in Participants With Alzheimer's Disease Who Had Previously Participated in the Aducanumab Studies 221AD103, 221AD301, 221AD302 and 221AD205

  NCT04241068· Phase 3· Biogen· Source

• Completed

  Optimize PRO Study

  NCT04091048· Medtronic Cardiovascular· Source

• Completed

  Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT

  NCT04173533· Phase 3· University of Birmingham· Source

• Completed

  A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens

  NCT03412565· Phase 2· Janssen Research & Development, LLC· Source

• Completed

  Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers

  NCT01597219· Phase 2· University College, London· Source