St Louis

The trials here

What the 13 trials at this site are about, from their registry records.

Conditions

• Amyloidosis5 trials
• Uveitis2 trials
• Alzheimer disease1 trial
• Crohn's disease1 trial
• Down syndrome1 trial
• High blood pressure1 trial
• Metastatic breast cancer1 trial
• Sarcoidosis1 trial

Phase

• Phase 36 trials
• Phase 24 trials
• Phase 1/21 trial
• Phase 2/31 trial

Status

• Recruiting5 trials
• Completed4 trials
• Active, not recruiting2 trials
• Enrolling by invitation1 trial
• Not yet recruiting1 trial

Lead sponsor

• Alnylam Pharmaceuticals8 trials
• Priovant Therapeutics, Inc.3 trials
• Arvinas Estrogen Receptor, Inc.1 trial
• Shattuck Labs, Inc.1 trial

Running trials

• Recruiting

  A Study of SL-325 in Crohn's Disease Patients

  NCT07753850· Phase 2· Shattuck Labs, Inc.· Source

  Contact: Shattuck Medical Director

• Recruiting

  A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

  NCT07636811· Phase 2· Alnylam Pharmaceuticals· Source

• Recruiting

  DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

  NCT07358078· Alnylam Pharmaceuticals· Source

• Recruiting

  Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  NCT07181109· Phase 3· Alnylam Pharmaceuticals· Source

• Recruiting

  TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

  NCT07052903· Phase 3· Alnylam Pharmaceuticals· Source

• Recruiting

  A Study of Brepocitinib in Adults With Cutaneous Sarcoidosis

  NCT06978725· Phase 2/3· Priovant Therapeutics, Inc.· Source

  Contact: Clinical Trial Administrator

• Enrolling by invitation

  A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

  NCT06679946· Phase 3· Alnylam Pharmaceuticals· Source

• Active, not recruiting

  A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

  NCT06431373· Phase 3· Priovant Therapeutics, Inc.· Source

• Active, not recruiting

  A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

  NCT06393712· Phase 2· Alnylam Pharmaceuticals· Source

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Amyloidosis3 recruiting
• Alzheimer disease1 recruiting
• Crohn's disease1 recruiting
• Down syndrome1 recruiting
• High blood pressure1 recruiting
• Sarcoidosis1 recruiting

Closed trials

• Completed

  A Study of Brepocitinib in Adults With Active Non-Infectious Non-Anterior Uveitis

  NCT05523765· Phase 2· Priovant Therapeutics, Inc.· Source

• Completed

  A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Participants With ER+/HER2- Locally Advanced or Metastatic Breast Cancer

  NCT04072952· Phase 1/2· Arvinas Estrogen Receptor, Inc.· Source

• Completed

  APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

  NCT03997383· Phase 3· Alnylam Pharmaceuticals· Source

• Completed

  HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

  NCT03759379· Phase 3· Alnylam Pharmaceuticals· Source