Toronto General Hospital

Running trials

• Not yet recruiting

  Adding Acetazolamide on Top of SGLT2 Inhibition in Persons With Type 2 Diabetes

  NCT07902726· Phase 2· Source

• Recruiting

  Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions

  NCT07654283· Phase 2· Source

• Recruiting

  Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy

  NCT07518862· Source

• Recruiting

  JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year

  NCT06930521· Source

• Enrolling by invitation

  Digital Education in Colorectal Cancer Patients

  NCT07686133· Source

• Recruiting

  A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor

  NCT07187401· Phase 1/2· Source

• Recruiting

  Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With Idiopathic Pulmonary Fibrosis

  NCT07284459· Phase 2· Source

• Recruiting

  A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

  NCT07165028· Phase 3· Source

• Recruiting

  Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

  NCT06957366· Source

• Recruiting

  Prevail Global Study

  NCT06535854· Source

• Recruiting

  Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant

  NCT06725121· Phase 1/2· Source

• Recruiting

  An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer

  NCT06693336· Phase 2· Source

• Recruiting

  Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

  NCT06217302· Phase 3· Source

• Active, not recruiting

  A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis

  NCT06558279· Phase 3· Source

• Recruiting

  meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis

  NCT05715814· Phase 3· Source

• Active, not recruiting

  EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

  NCT06531824· Phase 3· Source

• Not yet recruiting

  EASE-SOT Pilot Study

  NCT06396702· Source

• Active, not recruiting

  The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

  NCT06383390· Phase 3· Source

• Active, not recruiting

  i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

  NCT06480500· Phase 2· Source

• Recruiting

  The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients

  NCT05938712· Phase 2· Source

• Recruiting

  Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

  NCT06051617· Phase 3· Source

• Recruiting

  Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial

  NCT05955924· Phase 3· Source

• Recruiting

  A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV

  NCT05495906· Phase 4· Source

• Recruiting

  The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

  NCT05427370· Source

• Recruiting

  Type 1 Diabetes Virtual Self-management Education and Support

  NCT05756829· Source

• Active, not recruiting

  Symptom Management in Patients on Dialysis

  NCT05515991· Source

• Recruiting

  Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

  NCT04124120· Source

• Active, not recruiting

  TrEatment Approach in the Multimodal Era Registry

  NCT05629052· Source

• Recruiting

  A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

  NCT05744921· Phase 3· Source

• Active, not recruiting

  Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

  NCT05478304· Source

• Enrolling by invitation

  An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

  NCT05667493· Phase 3· Source

• Active, not recruiting

  Semaglutide vs Sitagliptin

  NCT05195944· Phase 4· Source

• Enrolling by invitation

  Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

  NCT04905693· Phase 3· Source

• Active, not recruiting

  A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)

  NCT05500222· Phase 3· Source

• Active, not recruiting

  A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

  NCT05133531· Phase 3· Source

• Active, not recruiting

  Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion

  NCT05069558· Source

• Active, not recruiting

  A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

  NCT05071300· Phase 3· Source

• Active, not recruiting

  A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis

  NCT05070858· Phase 3· Source

• Active, not recruiting

  A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

  NCT05050136· Phase 2· Source

• Recruiting

  A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

  NCT04951622· Phase 3· Source

• Active, not recruiting

  Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

  NCT04763200· Source

• Enrolling by invitation

  Ex-Vivo COF Study for Lung Cancer Observation

  NCT04534413· Source

• Recruiting

  Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

  NCT04045665· Phase 3· Source

• Active, not recruiting

  AMPLATZER PFO Occluder Post Approval Study

  NCT03309332· Source

• Recruiting

  Randomization of Single vs Multiple Arterial Grafts

  NCT03217006· Source

• Recruiting

  The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  NCT03142152· Source

• Active, not recruiting

  Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)

  NCT03301506· Phase 3· Source

• Active, not recruiting

  Long Term Follow Up for CTSN Mitral Valve Repair Studies

  NCT03066050· Source

• Active, not recruiting

  Mindfulness Based Eating Awareness Training for Bariatric Surgery Patients

  NCT03488966· Source

• Active, not recruiting

  Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases

  NCT02864485· Source

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Coronary artery disease4 recruiting
• Heart failure4 recruiting
• Lung cancer3 recruiting
• Type 1 diabetes3 recruiting
• Atrial fibrillation2 recruiting
• Chronic kidney disease2 recruiting
• Idiopathic pulmonary fibrosis2 recruiting
• Type 2 diabetes2 recruiting
• Amyloidosis1 recruiting
• Colorectal cancer1 recruiting
• Fatty liver disease (MASLD/MASH)1 recruiting
• Hepatitis B1 recruiting
• HIV1 recruiting
• Liver and biliary tract cancer1 recruiting
• Melanoma1 recruiting
• Myasthenia gravis1 recruiting
• Primary biliary cholangitis1 recruiting
• Stroke1 recruiting

Researchers

No researcher is linked here yet.

Closed trials

• Completed

  A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

  NCT06926660· Phase 2· Source

• Completed

  A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)

  NCT06335303· Phase 2· Source

• Completed

  Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

  NCT06247735· Phase 2· Source

• Completed

  Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

  NCT05861453· Phase 2· Source

• Completed

  Acorai Machine Learning Generalization (MLG) Study

  NCT05835024· Source

• Completed

  A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

  NCT05536804· Phase 2· Source

• Completed

  TESTING -ON Post-Trial ObservatioNal Cohort Study

  NCT05434325· Source

• Completed

  Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria

  NCT05570305· Phase 2· Source

• Completed

  Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression

  NCT05339074· Phase 2· Source

• Completed

  Ketamine for Treatment-Resistant Bipolar Disorder

  NCT05004896· Phase 2· Source

• Completed

  An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants

  NCT05275023· Phase 2· Source

• Terminated

  THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS)

  NCT05033314· Phase 3· Source

• Completed

  PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP)

  NCT05097430· Source

• Completed

  Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis

  NCT04708782· Phase 3· Source

• Completed

  A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus Infection

  NCT04585789· Phase 2· Source

• Completed

  A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

  NCT04439539· Phase 2· Source

• Completed

  CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

  NCT04136171· Phase 3· Source

• Completed

  A Wearable and a Self-management Application for Chronic Obstructive Pulmonary Disease (COPD) Patients at Home

  NCT03857061· Source

• Completed

  EMPA-KIDNEY (The Study of Heart and Kidney Protection With Empagliflozin)

  NCT03594110· Phase 3· Source

• Completed

  Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

  NCT00673842· Phase 3· Source