Frontlight ResearchEarly access
Taking people in BelgiumPhase 1
Tests a radioactive drug in adults with advanced colorectal, breast, lung or pancreatic cancer
Tests a radioactive drug, Lu-NNS309, in adults with advanced cancers.
Key facts
- Who runs it
- Novartis Pharma AG
- Where
- Anderlecht, BelgiumSee the siteAlso in 5 other countries, 15 sites
- Trial code
- EU 2023-510356-23-00
- U1111-1325-8631
- Registry title
- Phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-NNS309 in patients with pancreatic, lung, breast and colorectal cancers.
- Status
- Recruiting
- Phase
- Phase 1
- People taking part
- 76 people, planned
- Started
- 18 Jul 2025
- Expected to end
- 26 Jun 2030
- Type of study
- Interventional
- Record updated
- 12 May 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with advanced pancreatic, lung, breast or colorectal cancer that cannot be removed by surgery. It tests the safety and early effect of [177Lu]Lu-NNS309.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Locally advanced and cannot be removed by surgery, or metastatic: pancreatic ductal adenocarcinoma, non-small cell lung cancer, breast cancer or colorectal cancer.
Where in Belgium
Also in 5 other countries, 15 sites
- Institut Jules BordetAnderlecht, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record
Print a page for my doctorData and sources
- Registry record
- Listed on the EU's official list of trials (CTIS).
- Plain-language title
- Tests a radioactive drug in adults with advanced colorectal, breast, lung or pancreatic cancerGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 9 November 2026.
- Record updated
- 12 May 2026