Colorectal cancer trials in Belgium

In Belgium 77 Also abroad 1930

77 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Outcomes of Knife-Assisted Full-Thickness Resection for Rectal Lesions: A Multicenter Study
Where
Ghent
Age
18 years and over
People
150
Run by
University Hospital, Ghent
See details and how to joinNCT07923682
Phase 1/2Taking people
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Where
Brussels, Edegem, Leuven, Libramont-Chevigny, Liège, Namur
Age
18 years and over
People
910 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06324357
Phase 3Taking people
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Where
Brussels, Ghent, Haine-Saint-Paul, Kortrijk
Age
18 years and over
People
900 worldwide
Run by
Summit Therapeutics
See details and how to joinNCT07228832
Phase 3Taking people
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
Where
Charleroi, Edegem, Leuven, Sint-Lambrechts-Woluwe
Age
18 years and over
People
1,020 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07549412 · EU 2025-524648-37-00
Phase 1/2Taking people
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
Where
Anderlecht, Edegem, Leuven, Sint-Lambrechts-Woluwe
Age
18 years and over
People
225 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT05379595 · EU 2023-506517-22-00
Phase 1Taking people
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Where
Charleroi
Age
18 years and over
People
130 worldwide
Run by
Sairopa B.V.
See details and how to joinNCT05856981
Phase 3Taking people
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Where
Anderlecht, Edegem, Gent, Kortrijk, La Louvière, Leuven, Liège
Age
18 years and over
People
1,000 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06662786 · EU 2024-513852-13-00
Phase 3Taking people
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Where
Anderlecht, Edegem, Kortrijk, La Louvière, Leuven, Liège
Age
18 years and over
People
700 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06750094 · EU 2024-513853-66-00
Phase 1/2Taking people
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Where
Anderlecht, Gent, Namur, Sint-Lambrechts-Woluwe
Age
18 years and over
People
560 worldwide
Run by
Genmab
See details and how to joinNCT03526835 · EU 2024-513627-16-01
Phase 1/2Taking people
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
Where
Brussels
Age
18 years and over
People
160 worldwide
Run by
Eikon Therapeutics
See details and how to joinNCT07262619 · EU 2026-525248-13-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Where
Edegem, Gent, Jette, Leuven, Sint-Lambrechts-Woluwe, Yvoir
Age
18 years and over
People
700 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07284849 · EU 2025-523735-19-00
Phase 2Taking people
Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer
Where
Anderlecht, Bonheiden, Ghent, Leuven, Liège, Ostend, Woluwe-Saint-Lambert
Age
18 years and over
People
100 worldwide
Run by
Solstice Oncology, Inc.
See details and how to joinNCT07808151 · EU 2026-527233-58-00
Phase 3Not yet taking people in Belgium
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer.
Where
Anderlecht, Bonheiden, Charleroi, La Louvière, Libramont-Chevigny, Namur, Roeselare, Sint-Lambrechts-Woluwe, Yvoir
Age
18 years and over
People
450 worldwide
Run by
Genmab A/S
See details and how to join2026-525883-17-00 · EU 2026-525883-17-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Charleroi, Gent, Leuven, Liège, Sint-Lambrechts-Woluwe
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
No phaseTaking people
Biopsy-Resection Agreement of Peritoneal Histopathological Growth Patterns in Colorectal Peritoneal Metastases: A Prospective Observational Pilot Study
Where
Brussels
Age
Up to 100 years
People
30
Run by
Jules Bordet Institute
See details and how to joinNCT07474025
Phase 2/3Taking people
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Where
Bonheiden, Edegem, Leuven, Roeselare, Sint-Lambrechts-Woluwe
Age
18 years and over
People
990 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07221357 · EU 2025-523224-45-00
Phase 1Taking people
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
Where
Brussels, Ghent
Age
18 years and over
People
280 worldwide
Run by
Vividion Therapeutics, Inc.
See details and how to joinNCT06004245 · EU 2023-503170-20-01
Phase 2Taking people
A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum
Where
Brussels, Ghent, La Louvière, Leuven, Roeselare
Age
18 years and over
People
140 worldwide
Run by
Vividion Therapeutics, Inc.
See details and how to joinNCT07811193 · EU 2026-525507-26-00
Phase 1/2Taking people
First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer
Where
Brussels
Age
18 years to 75 years
People
90 worldwide
Run by
Brenus Pharma
See details and how to joinNCT06934538
Phase 1/2Taking people
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Where
Bonheiden, Brussels, Leuven, Roeselare
Age
18 years and over
People
346 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06885034
Phase 3Taking people
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Where
Anderlecht, Bonheiden, Charleroi, Edegem, Gent, Jette, Leuven, Roeselare, Sint-Lambrechts-Woluwe, Yvoir
Age
18 years and over
People
990 worldwide
Run by
AbbVie
See details and how to joinNCT07525206 · EU 2025-521712-19-00
Phase 3Taking people
A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with FOLFOX versus Bevacizumab in Combination with FOLFOX for the First-line Treatment of Metastatic Colorectal Cancer (HARMONi-GI3)
Where
Anderlecht, Gent, Kortrijk, La Louvière, Sint-Lambrechts-Woluwe
Age
18 years and over
People
230 worldwide
Run by
Summit Therapeutics Inc.
See details and how to join2025-521587-35-00 · EU 2025-521587-35-00
Phase 2Taking people
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Where
Leuven, Liège, Sint-Lambrechts-Woluwe
Age
18 years and over
People
140 worldwide
Run by
AbbVie
See details and how to joinNCT07023289 · EU 2024-518015-19-00
Phase 3Taking people
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Where
Charleroi, Gent, Leuven, Roeselare
Age
18 years and over
People
800 worldwide
Run by
Pfizer
See details and how to joinNCT07222800 · EU 2025-523521-18-00
Phase 1Taking people
A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation
Where
Ghent
Age
18 years and over
People
130 worldwide
Run by
Bayer
See details and how to joinNCT07535112 · EU 2025-523648-11-00