Collects health information and samples from people with retinal eye diseases
Collects blood and tissue samples and health data from people with eye diseases.
Plain-language title generated from the registry record
Registry title: National Eye Institute Biorepository for Retinal Diseases
Key facts
- Where
- Bethesda, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 2 and 120 years old?
Source: NCT01496625, who can take part
Where in United States
- National Institutes of Health Clinical CenterBethesda, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Eye Institute (NEI)
- Trial code
- NCT01496625
- Record updated
- 26 October 2026
- Original description
Background:Read full original descriptionShow less
NEI Intramural Biorepository for Retinal Diseases
Background:
- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some people respond to treatment while others do not. Researchers want to collect physical samples and personal data to develop a National Eye Institute database.
Objectives:
- To collect health information and blood and tissue samples from people with and without eye diseases, to be used in research studies.
Eligibility:
* Individuals at least 2 years of age with different types of eye disease. * Healthy volunteers with no history of eye disease.
Design:
* Participants may be recruited from National Eye Institute studies or may be referred from other sources. * Participants will be screened with a physical exam and medical history. They will also have a full eye exam. Questions will be asked about family medical history, especially about eye disease. * Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and urine, may be collected as needed. Adult participants may also provide a skin sample. * Tissue or fluid from eye collected as part of eye care or treatment may also be added to the database. * No treatment will be provided as part of this study.
Exclusion: Have a systemic disease that compromises the ability to provide adequate ophthalmologic examination or treatment; Participants will not be eligible if they:; Are unable or unwilling to give informed consent that includes collection and study of at least one peripheral blood sample; Are unable or unwilling to give informed consent that includes use of NIH medical records and clinical samples for research.
INCLUSION CRITERIA:; Participants will be eligible if they:; Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children; Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected control suitable for comparison to participants with various retinal diseases, particularly AMD and diabetic retinopathy (taking into account matching factors such as age and past ocular history).