Inflammation versus sleep apnea severity in predicting heart and metabolism problems
Studies inflammation, heart and metabolic risk in obstructive sleep apnea.
Key facts
- Who runs it
- Milton S. Hershey Medical Center
- Where
- Hershey, United StatesSee the site
- Trial code
- Registry title
- Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index
- Status
- Enrolling by invitation
- People taking part
- 196 people, planned
- Started
- 1 Mar 2017
- Expected to end
- Dec 2027
- Type of study
- Observational
- Record updated
- 23 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with mild to moderate obstructive sleep apnea, where breathing stops or becomes shallow during sleep. It studies whether inflammation or apnea severity better predicts heart and metabolism problems.
- Age
- 18 years and older
- Sex
- Men and women
- Disease stage
- Mild to moderate obstructive sleep apnea (5≤ AHI <30). AHI counts breathing pauses per hour of sleep.
- Earlier treatment
- People currently using CPAP (a breathing machine for sleep) cannot join. People currently using steroids or anti-inflammatory medicine cannot join.
- Biomarker or test result
- BMI ≤ 45
Main reasons for not taking part
- AHI ≥ 30 or BMI >45
- Current use of steroids, anti-inflammatory medicine or CPAP
- Insulin dependent diabetes
- An autoimmune disorder
- Shift work
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Mild to moderate OSA (5≤ AHI <30)
- BMI ≤ 45
- Age ≥ 18
- Men \& Women
Who cannot take part
- Current use of steroids or anti-inflammatory medication
- Diagnosis of insulin dependent diabetes
- Diagnosis of autoimmune disorder
- AHI ≥ 30
- BMI >45
- Shiftwork
- Current use of CPAP
Where in United States
- Penn State College of Medicine, Penn State Milton S. Hershey Medical CenterHershey, United StatesEnrolling by invitation
About the trial
What the trial wants to find out
The purpose of the study is to compare the relative contribution of systemic inflammation vs. Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting cardiovascular and metabolic aberrations associated with mild-to-moderate obstructive sleep apnea.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index
- Plain-language title
- Inflammation versus sleep apnea severity in predicting heart and metabolism problemsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Record updated
- 23 April 2026