Obstructive sleep apnoea trials in United States

In United States 118 Also abroad 366

118 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Where
Bethesda, Indianapolis, Washington D.C.
Age
1 month to 99 years
People
1,500
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT05656365
Phase 2Taking people
DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.
Where
Anderson, Brandon, Chula Vista, Cincinnati, Dallas, Jacksonville, Marrero, Memphis, Orlando, Rockville, San Antonio, West Palm Beach
Age
18 years to 65 years
People
120
Run by
Incannex Healthcare Ltd
See details and how to joinNCT07635563
No phaseNot yet taking people in United States
Use of a Mandibular Advancement Appliance in Children With Obstructive Sleep Apnea
Where
Bethesda
Age
6 years to 17 years
People
25
Run by
National Institute of Dental and Craniofacial Research (NIDCR)
See details and how to joinNCT07902908
No phaseNot yet taking people in United States
Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers
Where
Detroit, West Los Angeles
Age
50 years and over
People
128
Run by
VA Office of Research and Development
See details and how to joinNCT07207473
Phase 3Taking people
A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)
Where
Bradenton, Cullman, Maplewood, Tomball
Age
18 years and over
People
258
Run by
Pfizer
See details and how to joinNCT07881757
Phase 2Not yet taking people in United States
Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.
Where
La Jolla
Age
18 years to 75 years
People
62
Run by
University of California, San Diego
See details and how to joinNCT07923760
No phaseTaking people
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Where
Bethesda
Age
3 years to 12 years
People
120
Run by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
See details and how to joinNCT05052216
Phase 1/2Taking people
DRonabinol Treatment of OSA
Where
Chicago
Age
Up to 65 years
People
120
Run by
VA Office of Research and Development
See details and how to joinNCT06477952
Phase 3Taking people
A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)
Where
Bradenton, Cullman, Dallas, Little Rock, Maplewood, Riverside, Southfield, Tomball
Age
18 years and over
People
258
Run by
Pfizer
See details and how to joinNCT07823608
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Where
Albuquerque, Aurora, Austin, Bowie, Buffalo, Cincinnati, Columbia, Cullman, Las Vegas, Lawrenceville, Long Beach, Los Alamitos, Maplewood, Miami, Pensacola, Riverside, San Antonio, Shavano Park, Shreveport, Snellville, Southfield, St Louis
Age
18 years and over
People
800 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07369011 · EU 2025-523769-11-00
No phaseEnrolling by invitation
Myofunctional Therapy for Obstructive Sleep Apnea
Where
Minneapolis
Age
18 years to 65 years
People
30
Run by
University of Minnesota
See details and how to joinNCT07301125
No phaseNot yet taking people in United States
Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea With Complete Concentric Collapse
Where
Boston
Age
18 years and over
People
20
Run by
Brigham and Women's Hospital
See details and how to joinNCT07898618
No phaseTaking people
The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study
Where
New York, Pittsburgh, Tucson
Age
55 years to 85 years
People
200
Run by
California Pacific Medical Center Research Institute
See details and how to joinNCT05988385
Phase 4Taking people
Impact GLP-1 Agonists Following Bariatric
Where
Columbia
Age
18 years and over
People
150
Run by
University of Missouri-Columbia
See details and how to joinNCT06132477
No phaseTaking people
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
Where
Miami
Age
55 years to 85 years
People
330
Run by
University of Miami
See details and how to joinNCT06089161
No phaseTaking people
OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
Where
San Diego
Age
18 years and over
People
194
Run by
VA Office of Research and Development
See details and how to joinNCT05156112
Phase 4Taking people
A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in Adults
Where
Baltimore, Miami, Redwood City, Tucson
Age
18 years and over
People
2,400
Run by
Sairam Parthasarathy
See details and how to joinNCT07679282
No phaseTaking people
Evaluation of the F&P Mask, US, 2026
Where
St Louis
Age
22 years and over
People
45
Run by
Fisher and Paykel Healthcare
See details and how to joinNCT07826429
No phaseTaking people
PMOS in OSA Pilot Study
Where
Chicago
Age
18 years to 40 years
People
10
Run by
University of Chicago
See details and how to joinNCT07871149
No phaseNot yet taking people in United States
Evaluation of F&P Mask, US, 2026
Where
Columbia
Age
22 years and over
People
45
Run by
Fisher and Paykel Healthcare
See details and how to joinNCT07847814
No phaseTaking people
Application of the Patient-reported Longitudinal Assessment Tool for OSA (PLATO) Questionnaire in Oral Appliance Therapy for Obstructive Sleep Apnea
Where
Henderson
Age
18 years and over
People
20
Run by
Nevada Dental Sleep
See details and how to joinNCT07789834
Phase 3Taking people
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Where
Atlanta, Bradenton, Chicago, Cincinnati, Columbia, DeSoto, DuBois, El Paso, Fargo, Gilbert, Houston, Lawrenceville, Naples, New York, Renton, San Antonio, Seattle, Sugar Land, West Palm Beach
Age
18 years and over
People
300 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07571109 · EU 2024-520443-16-00
No phaseTaking people
SUNOSI® (Solriamfetol) Pregnancy Registry
Where
Morrisville, Wilmington
People
1,731
Run by
Axsome Therapeutics, Inc.
See details and how to joinNCT06413420
No phaseNot yet taking people in United States
Pediatric/Adolescent WatchPAT 400 Reliability Pilot Study
Where
Hummelstown
Age
6 years to 18 years
People
35
Run by
Milton S. Hershey Medical Center
See details and how to joinNCT07851402
No phaseTaking people
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Where
San Francisco
Age
21 years and over
People
100
Run by
University of California, San Francisco
See details and how to joinNCT07220525