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Studying lung disease in people with early rheumatoid arthritis

Observes lung disease and possible warning markers in people with early rheumatoid arthritis.

Plain-language title generated from the registry record
Registry title: Early Rheumatoid Arthritis Lung Disease Study

Key facts

Where
Omaha, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 19 and 90 years old?

Source: NCT03192267, who can take part

Where in United States

  • University of Nebraska Medical CenterOmaha, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of Nebraska
Trial code
NCT03192267
Record updated
9 July 2026
Original description
Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.Read full original descriptionShow less

Early Rheumatoid Arthritis Lung Disease Study

Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.

Inclusion: 19-90 years of age; Able to give informed consent; Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years.

Exclusion: Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA); Pregnant.

ClinicalTrials.gov NCT03192267