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Studying why some headaches become chronic over time

Looks at brain scans, fluid and blood samples in people with chronic headaches.

Plain-language title generated from the registry record
Registry title: Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics

Key facts

Where
Stanford, United StatesSee the site

Where in United States

  • Stanford University School of MedicineStanford, United StatesTaking people

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  4. What happens if I want to stop?
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Trial details

Who runs it
Stanford University
Trial code
NCT03231241
Record updated
23 July 2025
Original description
Study is aimed at determining why some patients with episodic headache proceed to chronic daily or near daily headaches. The Investigators seek to discover differences in brain anatomy and function, composition of cerebrospinal fluid, blood products, genetics, and patient phenotypes that might help explain this process.Read full original descriptionShow less

SunStar Project to Explore the Chronification Process in Headache Through Functional Imaging, Deep Phenotyping, and Analysis of CSF of Blood Products

Study is aimed at determining why some patients with episodic headache proceed to chronic daily or near daily headaches. The Investigators seek to discover differences in brain anatomy and function, composition of cerebrospinal fluid, blood products, genetics, and patient phenotypes that might help explain this process.

Inclusion: Subjects must agree to sign informed consent; Subject must be able to or at least with some help willing to complete online questionnaires in English ; Willing to comply with study instructions; must speak and understand English.

Exclusion: *Any neurological condition, at the discretion of the Principal Investigator (PI).

ClinicalTrials.gov NCT03231241