Migraine trials in United States

In United States 92 Also abroad 249

92 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Not yet taking people in United States
Visual Instillation of Sphenopalatine-block Intervention for ONgoing Migraine
Where
Springfield
Age
18 years and over
People
74
Run by
Association of Migraine Disorders
See details and how to joinNCT07764783
No phaseEnrolling by invitation
App-based Breathing Program for Migraine Relief
Where
Phoenix
Age
18 years and over
People
30
Run by
Arizona State University
See details and how to joinNCT07297901
No phaseTaking people
Marine Lipids Ease Painful TMD
Where
Chapel Hill
Age
18 years and over
People
100
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT07437313
No phaseTaking people
Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain
Where
Aurora
Age
12 years to 17 years
People
72
Run by
University of Colorado, Denver
See details and how to joinNCT07513662
Phase 2Taking people
Study of EVO756 in Adults With Migraine
Where
Amherst, Ann Arbor, Asheville, Atlanta, Austin, Buena Park, Canton, Centerville, Chandler, Charleston, Crab Orchard, Dallas, Decatur, Denver, Farmington Hills, Foxborough, Franklin, Fresno, Houston, Jacksonville, La Jolla, Los Angeles, McLean, Miami, New Haven, Orlando, Papillion, Raleigh, Stamford, Tampa, Toms River, Walnut Creek, Westborough, West Palm Beach
Age
18 years to 64 years
People
330 worldwide
Run by
Evommune, Inc.
See details and how to joinNCT07616128
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Where
Albuquerque, Allentown, Amherst, Ann Arbor, Atlanta, Austin, Bardstown, Birmingham, Boston, Bountiful, Brooklyn, Centennial, Chalmette, Chandler, Charlotte, Chattanooga, Chicago, City of Saint Peters, Colorado Springs, Colton, Columbus, Commack, Culver City, Cypress, Dallas, Draper, Edmond, Encino, Flossmoor, Fort Collins, Greensboro, Gulfport, Hazelwood, Houston, Irvine, Kansas City, Kenosha, Lampasas, Las Vegas, Lexington, Little Rock, Los Angeles, Manlius, Marietta, Milford, Minneapolis, Mission Viejo, Mobile, Morgantown, Naperville, Nashville, New Orleans, Newport News, New York, Norfolk, North Charleston, North Las Vegas, Oceanside, Ogden, Oklahoma City, Overland Park, Philadelphia, Pikesville, Pittsburgh, Plano, Pomona, Portland, Raleigh, Reno, Ridgeland, Riverside, Riverton, Rochester, Salt Lake City, San Diego, Scottdale, Seattle, Shelby, Sherman Oaks, Smithfield, Springfield, Spring Valley, St Louis, Stockbridge, Tulsa, Walnut Creek, Waltham, Waterbury, Waxahachie, West Chester, West Covina, West Des Moines, West Hills, Wichita, Williamsville, Yukon
Age
18 years to 75 years
People
1,800
Run by
TriGemX Bio, Inc.
See details and how to joinNCT07645924
Phase 3Taking people
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Where
Albuquerque, Allentown, Amherst, Ann Arbor, Atlanta, Austin, Bardstown, Birmingham, Boston, Bountiful, Brooklyn, Centennial, Chalmette, Chandler, Charlotte, Chattanooga, Chicago, City of Saint Peters, Colorado Springs, Colton, Columbus, Commack, Culver City, Cypress, Dallas, Draper, Edmond, Encino, Flossmoor, Fort Collins, Greensboro, Gulfport, Hazelwood, Houston, Irvine, Kansas City, Kenosha, Lampasas, Las Vegas, Lexington, Little Rock, Los Angeles, Manlius, Marietta, Milford, Minneapolis, Mission Viejo, Mobile, Morgantown, Naperville, Nashville, New Orleans, Newport News, New York, Norfolk, North Charleston, North Las Vegas, Oceanside, Ogden, Oklahoma City, Overland Park, Philadelphia, Pikesville, Pittsburgh, Plano, Pomona, Portland, Raleigh, Reno, Ridgeland, Riverside, Riverton, Rochester, Salt Lake City, San Diego, Scottdale, Seattle, Shelby, Sherman Oaks, Smithfield, Springfield, Spring Valley, St Louis, Stockbridge, Tulsa, Walnut Creek, Waltham, Waterbury, Waxahachie, West Chester, West Covina, West Des Moines, West Hills, Wichita, Williamsville, Yukon
Age
18 years and over
People
1,000
Run by
TriGemX Bio, Inc.
See details and how to joinNCT07674654
Phase 3Taking people
A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Where
Ames, Anderson, Atlanta, Aurora, Austin, Beachwood, Beaumont, Blue Ash, Boise, Canoga Park, Cary, Chula Vista, Cincinnati, Columbus, Dallas, Denver, DeSoto, El Paso, Fall River, Fargo, Fountain Valley, Foxborough, Fullerton, Gaffney, Glendale, Gurnee, Hallandale, Indianapolis, Lake Jackson, Lakeland, Las Vegas, Little Rock, Long Beach, Lynwood, Merrillville, Miami, Missoula, Morehead City, Norcross, Norfolk, Northridge, Ocoee, Omaha, Orlando, Pasadena, Phoenix, Providence, Raleigh, Redding, Salt Lake City, San Antonio, San Diego, San Francisco, Santa Ana, Savannah, Sioux City, Skokie, Stamford, Sugar Land, Tampa, Tomball, Toms River, Van Nuys, West Palm Beach, Wilmington, Winston-Salem
Age
18 years to 75 years
People
1,500
Run by
TriGemX Bio, Inc.
See details and how to joinNCT07816367
No phaseTaking people
Dietary Intervention for Migraine Relief
Where
Washington D.C.
Age
18 years to 75 years
People
40
Run by
American University
See details and how to joinNCT07360405
No phaseTaking people
Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to Rimegepant
Where
Wilmington
Age
0 years and over
People
780
Run by
Pfizer
See details and how to joinNCT05046613
Phase 3Taking people
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Where
Akron, Amherst, Anaheim, Ann Arbor, Apopka, Atlanta, Aurora, Austin, Bellaire, Bellevue, Birmingham, Boston, Brunswick, Burlington, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Colorado Springs, Columbus, Commack, Costa Mesa, Cromwell, Culver City, Cutler Bay, Dallas, Decatur, DeLand, East Greenwich, El Paso, Everett, Flowood, Fountain Valley, Fresno, Frisco, Gainesville, Grand Rapids, Grants Pass, Great Falls, Great Neck, Greensboro, Greenville, Hartford, Houston, Kalamazoo, Kalispell, Kansas City, Kenosha, Kingsport, La Jolla, Lake City, Lakeland, Lake Success, Lexington, Lincoln, Long Beach, Los Angeles, Madison, Memphis, Miami, Mineola, Missoula, Naperville, Naples, Nashville, Neptune City, New Orleans, New York, Norfolk, North Canton, North Hollywood, Oklahoma City, Omaha, Orange, Orange Park, Orlando, Overland Park, Ozark, Pembroke Pines, Philadelphia, Plano, Pomona, Port Jefferson Station, Portland, Richmond, Rochester, Royal Oak, Sacramento, Salt Lake City, San Bernardino, Scottsdale, Seattle, Shreveport, Sioux City, Springfield, Stamford, Tampa, Tempe, The Bronx, Tulsa, Upland, Walnut Creek, Waltham, Washington D.C., West Des Moines, Westfield, West Palm Beach, Wilmington
Age
6 years to 17 years
People
2,100 worldwide
Run by
Pfizer
See details and how to joinNCT04649242 · EU 2024-512743-23-00
Phase 3Taking people
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Where
Amherst, Anaheim, Ann Arbor, Atlanta, Aurora, Austin, Bellaire, Bellevue, Brunswick, Charlotte, Charlottesville, Chicago, Cincinnati, Clarksville, Cleveland, Colorado Springs, Commack, Cromwell, Culver City, Dallas, Dayton, Decatur, East Greenwich, El Paso, Fresno, Frisco, Grand Junction, Grand Rapids, Grants Pass, Great Falls, Greensboro, Greenville, Greer, Houston, Kalamazoo, Kalispell, Kansas City, La Jolla, Lexington, Lincoln, Long Beach, Madison, Memphis, Miami, Missoula, Naperville, Nashville, Neptune City, New Orleans, New York, Norfolk, North Hollywood, Oklahoma City, Omaha, Orange Park, Orlando, Ozark, Philadelphia, Plano, Pomona, Port Jefferson Station, Portland, Richmond, Royal Oak, Sacramento, Salt Lake City, San Bernardino, Scottsdale, Seattle, Springfield, Stamford, Tampa, Tempe, Upland, Walnut Creek, Waltham, Washington D.C., West Des Moines, Westfield, West Palm Beach
Age
6 years to 17 years
People
600 worldwide
Run by
Pfizer
See details and how to joinNCT04743141 · EU 2024-512744-32-00
Phase 1Taking people
A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department
Where
Tampa
Age
18 years and over
People
100
Run by
University of South Florida
See details and how to joinNCT07667621
Early phase 1Taking people
Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness
Where
Waltham
Age
13 years to 25 years
People
12
Run by
Boston Children's Hospital
See details and how to joinNCT07374640
No phaseNot yet taking people in United States
Validation of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) for Adolescents
Where
Needham, Waltham, Weymouth
Age
10 years to 20 years
People
70
Run by
Boston Children's Hospital
See details and how to joinNCT07532109
No phaseTaking people
Overlapping Pain Trajectory Study
Where
Cincinnati
Age
10 years to 19 years
People
420
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT05752396
No phaseEnrolling by invitation
Migraine Medication Effects on Urinary Symptoms
Where
Cleveland
Age
18 years and over
People
200
Run by
The Cleveland Clinic
See details and how to joinNCT06212661
Phase 4Taking people
Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
Where
Aurora, Charlotte, Columbus, Edison, Flagstaff, Hazel Green, Hollywood, Hyde Park, Jacksonville, Kingston, Los Angeles, Manhasset, Marshfield, McAllen, Miami, Milwaukee, Morgantown, Nashville, New York, Ogden, Omaha, Overland Park, Palm Springs, Philadelphia, Phoenix, Pomona, Portland, Providence, Reno, Rochester, Salisbury, St Louis, Winston-Salem
Age
18 years to 70 years
People
1,335
Run by
Mayo Clinic
See details and how to joinNCT06972056
Phase 3Taking people
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
Where
Amherst, Ann Arbor, Atlanta, Baltimore, Charlotte, Cincinnati, Commack, Gainesville, Grand Rapids, Gulf Breeze, Hialeah, Huntington, Lexington, Loxahatchee Groves, New Haven, Norfolk, Oklahoma City, San Antonio, Stamford, Tacoma, Tampa, Washington D.C.
Age
12 years to 17 years
People
285 worldwide
Run by
H. Lundbeck A/S
See details and how to joinNCT04965675 · EU 2024-510656-13-00
Phase 3Taking people
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
Where
Amherst, Augusta, Boise, Charleston, Chicago, Cincinnati, Clinton, Colorado Springs, Columbia, Dallas, Detroit, Edgewater, Fayetteville, Fort Collins, Fort Smith, Frisco, Grand Island, Greenville, Hawthorne, Hialeah, Hollywood, Houston, Lake Jackson, La Mesa, McAllen, Minneapolis, Nashville, New Orleans, Oklahoma City, Ormond Beach, Papillion, Portsmouth, Reno, San Antonio, Sandy Springs, Savannah, Sherman, Sioux Falls, Snellville, Tamarac, Tampa, The Bronx, Tomball, Victoria, Washington D.C.
Age
6 years to 17 years
People
640 worldwide
Run by
Pfizer
See details and how to joinNCT05156398 · EU 2024-512382-13-00
Phase 3Taking people
A Study With Eptinezumab in Children and Adolescents (6 to 17 Years) With Chronic or Episodic Migraine
Where
Akron, Amherst, Ann Arbor, Baltimore, Charlotte, Cincinnati, Commack, Gainesville, Grand Rapids, Gulf Breeze, Hialeah, Huntington, Lexington, Loxahatchee Groves, Milwaukee, New Haven, Norfolk, San Antonio, Stamford, Tampa
Age
6 years to 17 years
People
600 worldwide
Run by
H. Lundbeck A/S
See details and how to joinNCT05164172 · EU 2022-502917-27-00
Phase 3Taking people
A Study of Eptinezumab in Pediatric Participants With Episodic Migraine
Where
Akron, Ann Arbor, Atlanta, Baltimore, Charlotte, Cincinnati, Commack, Gulf Breeze, Hialeah, Lexington, Milwaukee, Norfolk, San Antonio, Stamford, Tampa
Age
6 years to 17 years
People
315 worldwide
Run by
H. Lundbeck A/S
See details and how to joinNCT05897320 · EU 2022-502538-14-00
Phase 4Taking people
A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine
Where
Abington, Ann Arbor, Austin, Boca Raton, Burnsville, Canoga Park, Chicago, Dallas, Fresno, Greensboro, Indianapolis, Lake Jackson, Las Vegas, Los Angeles, McLean, Miami, Orlando, Ridgeland, Worcester
Age
18 years and over
People
400 worldwide
Run by
Pfizer
See details and how to joinNCT07609914
Phase 3Taking people
A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine
Where
Ann Arbor, Austin, Boca Raton, Canoga Park, City of Saint Peters, Dallas, Fresno, Indianapolis, Los Angeles, Memphis, Oklahoma City, Overland Park, Papillion, Salt Lake City, Scottsdale, Williamsville, Winter Park, Worcester
Age
18 years and over
People
400 worldwide
Run by
Pfizer
See details and how to joinNCT07729462 · EU 2026-525295-25-00
Phase 3Taking people
A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years
Where
Amherst, Anaheim, Ann Arbor, Austin, Bountiful, Clinton, Evansville, Fayetteville, Fresno, Greensboro, Gulf Breeze, Houston, Huntsville, Kingwood, Lakeland, Little Rock, Long Beach, Miami, Nashua, Nashville, Oceanside, Papillion, Philadelphia, Ridgeland, Salt Lake City, San Jose, Scottdale, Smithfield, Walnut Creek, Waxahachie, Weston, Winter Park
Age
12 years to 17 years
People
420 worldwide
Run by
AbbVie
See details and how to joinNCT06810505 · EU 2024-513836-28-00