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Enrolling by invitationNo phase

Long-term safety of brodalumab compared with other psoriasis treatments

Follows adults with moderate-to-severe psoriasis treated with brodalumab or other therapies.

Plain-language title generated from the registry record
Registry title: LTS of Siliq vs. Other Therapies Treating of Adults With Moderate-to-Severe Psoriasis

Key facts

Where
Bridgewater, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 99 years old?

Source: NCT03254667, who can take part

Where in United States

  • RegistryBridgewater, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Bausch Health Americas, Inc.
Trial code
NCT03254667
Record updated
16 September 2025
Original description
Prospective, Observational Study to Assess the Long-Term Safety of Brodalumab Compared with Other Therapies in the Treatment of Adults with Moderate-to-Severe PsoriasisRead full original descriptionShow less

Prospective, Observational Study Brodalumab Compared With Other Therapies in the Treatment of Adults With Moderate-to-Severe Psoriasis Who Are Candidates for Systemic Therapy or Phototherapy in the Course of Actual Clinical Care

Prospective, Observational Study to Assess the Long-Term Safety of Brodalumab Compared with Other Therapies in the Treatment of Adults with Moderate-to-Severe Psoriasis

Inclusion: Diagnosis and main criteria for inclusion: a subject must have moderate to severe psoriasis diagnosed by a dermatologist; Must be at least 18 years of age or older; Started on or switched to a systemic psoriasis treatment within the previous 12 months. FDA-approved biologic treatments and select non-biologic treatments (eg, methotrexate, cyclosporine, or apremilast only) are permitted.

Exclusion: The subject is participating or planning to participate in a clinical trial with a non-marketed or marketed investigational drug (i.e. Phase I-IV drug trial); The subject is restarting the eligible medication less than 12 months since receiving the last dose; The subject is unable or unwilling to provide informed consent to participate in the registry.

ClinicalTrials.gov NCT03254667