Psoriasis trials in United States

In United States 69 Also abroad 274

69 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis
Where
Austin, Avon Park, Chicago, Clearwater, Cumberland, Duncansville, Frisco, Houston, Huntington Beach, Lebanon, Memphis, Middleburg Heights, Orlando, San Antonio, Skokie, Tamarac, Tampa, Tomball, Willowbrook
Age
18 years and over
People
300 worldwide
Run by
AbbVie
See details and how to joinNCT06865105
Early phase 1Enrolling by invitation
Thera-Clean® Microbubbles System in Patients With Skin Diseases
Where
Chicago
Age
2 years and over
People
20
Run by
Northwestern University
See details and how to joinNCT07050810
Phase 2Taking people
A Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Moderate to Severe Psoriatic Arthritis
Where
Colleyville, Corpus Christi, Duncansville, Huntington Beach, Katy, Memphis, Philadelphia, San Antonio
Age
18 years to 100 years
People
220
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07801495
Phase 1Taking people
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
Where
Albuquerque, Apple Valley, Baytown, Beckley, Bellevue, Chicago, Colleyville, Covina, Duncansville, Fort Collins, Fullerton, Jackson, Lansing, Mesquite, Murfreesboro, Ormond Beach, Peoria, Plano, Riverside, Rock Hill, San Leandro, South Miami, Spokane, Temecula, Upland, Vandalia, West Long Branch, Whittier, Zephyrhills
Age
18 years and over
People
392 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT07290036
Phase 4Taking people
Impact of Glucagon-like Peptide-1 (GLP-1) Analogs on Disease Outcomes in Psoriatic Arthritis: A Pragmatic Randomized Controlled Trial
Where
Milwaukee
Age
18 years and over
People
22
Run by
Medical College of Wisconsin
See details and how to joinNCT07111494
No phaseNot yet taking people in United States
Assessing Psoriasis Treatment Outcomes
Where
Winston-Salem
Age
18 years and over
People
15
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07391423
Phase 4Taking people
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Where
Ann Arbor, Bellaire, Bellevue, Boardman, Bowling Green, Brighton, Caledonia, Cary, Columbia, Dallas, Douglasville, East Windsor, Fountain Valley, Fremont, Hialeah, Hoboken, Hollywood, Houston, Huntersville, Indianapolis, Layton, Los Angeles, New York, Northridge, Pflugerville, Phoenix, Plainfield, Plymouth Meeting, Portland, Portsmouth, Reno, Rockville, San Antonio, Smyrna, Tampa, Webster, Wellington
Age
18 years and over
People
200
Run by
Eli Lilly and Company
See details and how to joinNCT06857942
No phaseTaking people
Metabolic Profiling of Immune Responses in Immune-mediated Diseases
Where
Bethesda
Age
18 years to 75 years
People
300
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT04864886
Phase 3Taking people
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Where
Atlanta, Cincinnati, Fort Worth, Indianapolis, Salt Lake City
Age
3 years to 64 years
People
196 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06663332 · EU 2023-509560-16-00
Phase 4Taking people
A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
Where
Chapel Hill
Age
18 years and over
People
10
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07654751
Phase 3Taking people
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Where
Alpharetta, Anderson, Arlington, Atlanta, Auburn Hills, Bentonville, Bexley, Birmingham, Boca Raton, Bowling Green, Brighton, Camp Hill, Canal Winchester, Canton, Cary, Castle Rock, Chapel Hill, Chicago, Clinton Township, Columbia, Coral Gables, Covington, Cypress, Dallas, Encinitas, Encino, Evansville, Exton, Fairborn, Fountain Valley, Fremont, Goodlettsville, Greenville, Hermitage, Hickory, Houston, Huntington Beach, Indianapolis, Kew Gardens, Lake Charles, Las Vegas, Los Angeles, Louisville, Maitland, Mason, Mayfield Heights, Medford, Medina, Metairie, Miami, Miami Lakes, Milford, Mill Creek, Murfreesboro, Nashville, New Albany, New Brighton, New City, New Orleans, New York, Norfolk, North Charleston, North Las Vegas, Northridge, Ocala, Oklahoma City, Omaha, Owensboro, Palmdale, Pasadena, Phoenix, Pittsburgh, Pomona, Portland, Portsmouth, Quincy, Rapid City, Rochester, Rockville, Rogers, Sacramento, San Antonio, San Diego, Santa Clarita, Santa Monica, Savannah, Scottsdale, Sherman Oaks, Skokie, Spokane, St Louis, Stony Brook, Sweetwater, Tampa, Teaneck, Tempe, The Bronx, Troy, Verona, Walnut Creek, Washington D.C., Waterford, Webster, Wilmington
Age
40 years and over
People
3,040 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07116967 · EU 2023-503766-24-00
Phase 3Taking people
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Where
Ammon, Atlanta, Birmingham, Canton, Clearwater, Clifton, Columbia, Detroit, Fountain Valley, Fremont, Goodlettsville, Hickory, Houston, Indianapolis, Las Vegas, Lee's Summit, Lorain, Los Angeles, Margate, Mayfield Heights, Metairie, Miami, Miami Lakes, Milford, Mill Creek, Murray, Nashville, New York, Norfolk, Northridge, Philadelphia, Phoenix, Robbinsville, Rockville, Sacramento, San Antonio, Sandy Springs, Southlake, Spokane, Tampa, The Bronx, Walnut Creek, Wheat Ridge
Age
12 years to 17 years
People
366 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06979453 · EU 2023-506296-97-00
Phase 2Taking people
An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
Where
Boston, Bowling Green, Cleveland, Cromwell, Detroit, Fountain Valley, Frisco, Houston, Los Angeles, Mason, Miami, New York, Norfolk, North Little Rock, Phoenix, Plainfield, Portland, Rockville, Rolling Meadows, San Diego, Santa Ana, Santa Monica, Webster
Age
18 years and over
People
240 worldwide
Run by
Oruka Therapeutics, Inc.
See details and how to joinNCT07449702 · EU 2026-526898-42-00
No phaseTaking people
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
Where
Akron, Albany, Ann Arbor, Atlanta, Augusta, Aurora, Birmingham, Boston, Burlington, Chapel Hill, Charleston, Charlotte, Chicago, Cincinnati, Cleveland, Columbus, Dallas, Durham, Fargo, Gainesville, Grand Rapids, Hackensack, Hartford, Hershey, Houston, Indianapolis, Iowa City, Jackson, Kansas City, Lake Success, Los Angeles, Louisville, Madison, Miami, Minneapolis, Morristown, Nashville, New Brunswick, New Haven, New York, Norfolk, Orlando, Palo Alto, Philadelphia, Phoenix, Pittsburgh, Portland, Providence, Rochester, Salt Lake City, San Diego, San Francisco, Seattle, Springfield, St Louis, St. Petersburg, Washington D.C., Wauwatosa, West Orange, Winston-Salem
Age
Up to 21 years
People
20,000 worldwide
Run by
Duke University
See details and how to joinNCT02418442
No phaseNot yet taking people in United States
Patient-Reported Outcomes Dashboard With Goal Setting to Support Shared Decision-Making in Inflammatory Arthritis
Where
Chicago
Age
18 years and over
People
160
Run by
Northwestern University
See details and how to joinNCT07865390
Phase 3Taking people
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Where
Albuquerque, Aventura, Baytown, Bellaire, Boca Raton, Brooklyn, Chandler, Clearwater, Cleveland, Cooper City, Coral Gables, Davie, Denver, Detroit, Fountain Valley, Grand Blanc, Hagerstown, Hialeah, Hickory, Houston, Howell, Jackson, Lake Charles, La Mesa, Lansing, Lubbock, Marietta, Mesquite, Miami, Middleburg Heights, Orlando, Orland Park, Ormond Beach, Phoenix, Plano, Plantation, Saint Clair Shores, Santa Fe, Sarasota, Schaumburg, Spokane, St Louis, Tamarac, Tampa, Thousand Oaks, Tujunga, Whittier, Wyomissing
Age
18 years and over
People
1,088 worldwide
Run by
Takeda
See details and how to joinNCT06671483 · EU 2024-513111-27-00
Phase 1Taking people
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Where
Atlanta, Baltimore, Bethesda, Birmingham, Boston, Chicago, City of Saint Peters, Columbus, Creve Coeur, Dallas, Detroit, Fairway, Fort Worth, Hays, Houston, Kansas City, Lawrence, Lee's Summit, Lexington, Mineola, New Brunswick, New Haven, New York, North Kansas City, Olathe, Overland Park, Palo Alto, Philadelphia, Pittsburg, Pittsburgh, Richardson, Richmond, Sacramento, Salina, Salt Lake City, St Louis, Topeka, Washington D.C., Westwood
Age
18 years and over
People
300 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03816345
No phaseTaking people
A Study to Assess Deucravacitinib Safety in Pregnancy
Where
La Jolla
People
900
Run by
Bristol-Myers Squibb
See details and how to joinNCT07017699
Phase 4Taking people
An Open Label Trial to Evaluate Efficacy and Safety of Roflumilast 0.3% Cream for Chronic Plaque and Nail Psoriasis
Where
Dallas
People
15
Run by
Modern Research Associates, PLLC
See details and how to joinNCT07725822
Phase 3Taking people
Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis
Where
Fremont, Glendale, Indianapolis, Miami, Portsmouth, Rochester, San Antonio, Spokane, Webster, Wilmington
Age
18 years to 65 years
People
300
Run by
Vanda Pharmaceuticals
See details and how to joinNCT07362017
Phase 1Taking people
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
Where
Boston, Chapel Hill, Durham, Milwaukee, Santa Monica, South Miami
Age
18 years and over
People
20 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT06888193 · EU 2024-518689-29-00
Phase 3Enrolling by invitation
A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Psoriatic Arthritis
Where
Avondale, Avon Park, Baytown, Charlotte, Clearwater, Duncansville, Jonesboro, Leland, Lubbock, Memphis, Mesa, Middleburg Heights, Phoenix, Scottsdale, Tampa, Tucson, Upland
Age
18 years and over
People
1,560
Run by
MoonLake Immunotherapeutics AG
See details and how to joinNCT07223138
Phase 3Taking people
A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis
Where
Bellaire, Canton, Charleston, Chula Vista, Fairborn, Fountain Valley, Hialeah, Mayfield Heights, Milwaukee, Rolling Meadows, San Antonio
Age
4 years to 17 years
People
110 worldwide
Run by
Takeda
See details and how to joinNCT07250802 · EU 2025-522567-15-00
Phase 3Taking people
Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis
Where
Baytown, Bellaire, Denver, Fountain Valley, Hagerstown, Hialeah, Houston, Jackson, La Mesa, Lubbock, Mesquite, Middleburg Heights, Plantation, The Woodlands, Thousand Oaks, Tucson
Age
18 years and over
People
1,182 worldwide
Run by
Takeda
See details and how to joinNCT07286058 · EU 2025-522586-30-00
Phase 4Taking people
The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease
Where
San Francisco
Age
18 years and over
People
50
Run by
University of California, San Francisco
See details and how to joinNCT07487831