Tests CPAP breathing device for high blood pressure lying flat in autonomic failure
Tests whether a breathing device lowers lying-down blood pressure in adults with autonomic failure.
Plain-language title generated from the registry record
Registry title: Treatment of Supine Hypertension in Autonomic Failure (CPAP)
Key facts
- Where
- Nashville, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT03312556, who can take part
Where in United States
- Autonomic Dysfunction Center/ Vanderbilt University Medical CenterNashville, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vanderbilt University Medical Center
- Trial code
- NCT03312556
- Record updated
- 9 November 2026
- Original description
Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.Read full original descriptionShow less
Treatment of Supine Hypertension in Autonomic Failure With Continuous Positive Airway Pressure
Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.
Inclusion: Patients with autonomic failure and with supine hypertension from all races.
Exclusion: High-risk patients (e.g. heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction); History of serious allergies or asthma; All medical students; Pregnant women.