High blood pressure trials in United States

In United States 313 Also abroad 847

313 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Treatment of Supine Hypertension in Autonomic Failure (CPAP)
Where
Nashville
Age
18 years to 85 years
People
12
Run by
Vanderbilt University Medical Center
See details and how to joinNCT03312556
No phaseTaking people
Gut Microbiota in Metabolic Surgery
Where
Nashville
Age
21 years to 65 years
People
300
Run by
Vanderbilt University Medical Center
See details and how to joinNCT05000996
No phaseTaking people
The REACH-OUT Trial
Where
Chicago
Age
18 years to 44 years
People
350
Run by
Northwestern University
See details and how to joinNCT07540143
No phaseEnrolling by invitation
Testing Implementation Strategies to Support Clinic Fidelity to an Outpatient Hypertension Bundle
Where
Burlington, Chapel Hill, Durham, Hillsborough, Raleigh
Age
0 years to 99 years
People
5,677
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT06002165
Phase 3Taking people
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Where
Albany, Ann Arbor, Arlington, Arvada, Atlanta, Augusta, Austell, Austin, Bethesda, Beverly Hills, Boca Raton, Boston, Boynton Beach, Braintree, Bridgeville, Brunswick, Buffalo, Burlington, Butler, Canoga Park, Canton, Champaign, Charleston, Chattanooga, Cincinnati, Columbia, Columbus, Concord, Conyers, Dallas, Decatur, Denver, Detroit, East Point, East Providence, Eatontown, Edgewater, Evansville, Exton, Fairhope, Fort Lauderdale, Fremont, Fullerton, Garden City, Greenville, Hickory, Hollywood, Honolulu, Houston, Humble, Hutchinson, Idaho Falls, Indianapolis, Inglewood, Iowa City, Jacksonville, Jacksonville Beach, Kansas City, Kenner, Kinston, Knoxville, Lake City, Lakeland, Langhorne, Las Vegas, Lawrenceville, Lewisville, Los Alamitos, Los Angeles, Manassas, Maywood, Media, Melbourne, Metairie, Miami Lakes, Morehead City, Nashville, New Bedford, New Bern, New Britain, Newport News, New York, Norfolk, Ocoee, Orangeburg, Pasadena, Pearland, Port Charlotte, Port Orange, Providence, Raleigh, Richmond, Riverdale, Riverview, Rockford, Rocky Mount, Saint Joseph, San Antonio, San Diego, Sanford, San Francisco, Seattle, South Salt Lake, Springfield, Stanford, Statesville, St Louis, Sun City, Tarzana, Tucson, Washington D.C., West Des Moines, West Monroe, Wichita, Wilmington, Winston-Salem, Woodbridge, Worcester
Age
18 years and over
People
5,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06742723 · EU 2023-506460-14-00
No phaseTaking people
Guiding Optimal Blood Pressure Management in Peritoneal Dialysis Pilot Trial
Where
San Francisco
Age
18 years and over
People
10
Run by
University of California, San Francisco
See details and how to joinNCT07910773
No phaseNot yet taking people in United States
A MOST Framework Trial Evaluating the MOst effectiVe Exercise Types for Blood Pressure Control
Where
Chicago
Age
18 years to 44 years
People
264
Run by
Northwestern University
See details and how to joinNCT07915752
No phaseTaking people
Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
Where
Buffalo, New Haven, Worcester
Age
18 years and over
People
6,030
Run by
Yale University
See details and how to joinNCT05884190
Early phase 1Enrolling by invitation
Truway Diagnostic Tools in Primary Care
Where
New York
People
200
Run by
Truway Health, Inc.
See details and how to joinNCT07209527
No phaseNot yet taking people in United States
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health
Where
Boynton Beach
Age
18 years and over
People
200
Run by
Florida International University
See details and how to joinNCT07918508
Phase 3Not yet taking people in United States
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Where
Albany, Amarillo, Austin, Bellaire, Bowling Green, Bristol, Buckley, Canton, Chicago, City of Saint Peters, Clearwater, Concord, Conyers, Costa Mesa, Cumberland, Dallas, Flint, Fullerton, Houston, Indianapolis, Kingsport, Lampasas, Longview, Louisville, Montclair, Morton, Nashville, Norman, North Charleston, Ocala, Orlando, Palm Springs, Portsmouth, Raleigh, Renton, Roswell, San Antonio, San Dimas, Savannah, Shavano Park, Skokie, Spartanburg, Springfield, Statesville, St Louis, Wadsworth, Waterbury, West Des Moines, Westfield, West Seneca
Age
18 years and over
People
1,408 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07919405
Phase 2Taking people
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Where
Alexander City, Asheboro, Bellaire, Birmingham, Bloomfield Hills, Boca Raton, Boston, Charleston, Charlotte, Cincinnati, Dallas, Decatur, Glendale, Indianapolis, Jacksonville, Las Vegas, Lawrenceville, Leesburg, Maitland, Methuen, Monroe, Munster, New Orleans, North Charleston, Orlando, Overland, Pasadena, Peachtree Corners, Plano, Port Orange, San Antonio, San Diego, San Jose, Sugar Land, Tampa, The Bronx, Tucson, Tulsa, Ventura, Vienna, Waterbury, West Hills
Age
18 years to 75 years
People
280
Run by
Retension Pharmaceuticals. Inc.
See details and how to joinNCT07142356
Phase 2Taking people
Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans
Where
Nashville
Age
18 years and over
People
20
Run by
Vanderbilt University Medical Center
See details and how to joinNCT07602166
No phaseNot yet taking people in United States
PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study
Where
Milwaukee
Age
18 years and over
People
60
Run by
Medical College of Wisconsin
See details and how to joinNCT05377320
Phase 2Taking people
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Where
Altamonte Springs, Buffalo, Cincinnati, Cutler Bay, Cypress, Dearborn, Foxborough, Glendora, Houston, Huntsville, Indianapolis, Kingwood, Las Vegas, Lombard, Maitland, Manassas, McKinney, North Charleston, Ogden, Olive Branch, Orlando, Reston, The Bronx, Tucson, West Chester, Woodstock, Yardley
Age
18 years and over
People
120 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07783802
Phase 4Taking people
Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome
Where
Canton, Jacksonville, Weslaco
Age
18 years and over
People
63
Run by
RECORDATI GROUP
See details and how to joinNCT07247162 · EU 2025-524649-28-00
Phase 4Taking people
Autonomic and Renal Contributions to Hypertension With ADT
Where
Richmond
Age
40 years and over
People
60
Run by
Virginia Commonwealth University
See details and how to joinNCT07848828
No phaseTaking people
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Where
Akron, Albany, Augusta, Cleveland, Dallas, Frederick, Irvine, Lancaster, Marietta, Munster, New York, Palo Alto, Rochester, Saint Cloud, San Antonio, Stuart, Tampa, Toledo, Weston, Wyoming
Age
18 years to 100 years
People
1,018
Run by
Zeenat Qureshi Stroke Institute
See details and how to joinNCT06402968
No phaseTaking people
Dry Weight Reduction Intervention Via Extra Ultrafiltration
Where
Seattle
Age
18 years and over
People
120
Run by
University of Washington
See details and how to joinNCT07637110
No phaseTaking people
Diabetes and Heart Disease Risk in Blacks
Where
Bethesda
Age
18 years to 70 years
People
2,000
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT00001853
No phaseNot yet taking people in United States
Care COMPASS Study
Where
Portland
Age
18 years and over
People
200
Run by
Fitbit LLC
See details and how to joinNCT07904793
No phaseEnrolling by invitation
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
Where
Akron, Ann Arbor, Atlanta, Augusta, Aurora, Baltimore, Birmingham, Boston, Brooklyn, Burlington, Chapel Hill, Charleston, Charlottesville, Chicago, Cincinnati, Columbus, Dallas, Hartford, Houston, Indianapolis, Iowa City, Kansas City, Lexington, Little Rock, Louisville, Lubbock, Madison, Miami, Milwaukee, Minneapolis, Nashville, New Haven, Omaha, Palo Alto, Philadelphia, Pittsburgh, Portland, Queens, Rochester, Salt Lake City, San Antonio, San Diego, Seattle, South Miami, Springfield, St Louis, Stony Brook, The Bronx, Washington D.C., Westchester, Winston-Salem
Age
0 Minutes to 2 weeks
People
8,000 worldwide
Run by
Indiana University
See details and how to joinNCT06823115
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Albany, Albuquerque, Anniston, Aurora, Austin, Avon, Baltimore, Beaver, Beverly Hills, Billings, Binghamton, Boca Raton, Bossier City, Bowling Green, Bridgeport, Bridgewater, Brownsville, Buffalo, Camp Hill, Canoga Park, Cary, Chandler, Chapel Hill, Chicago, Cincinnati, Clearwater, Columbus, Concord, Covington, Cutler Bay, Dakota Dunes, Dallas, Dearborn, DeLand, Doral, El Dorado, Elkhart, El Paso, Fairhope, Falls Church, Fargo, Fayette, Fleming Island, Flint, Forney, Fort Mill, Fort Myers, Fort Worth, Franklin, Fremont, Gaffney, Golden, Greenfield, Greenville, Guntersville, Hallandale, Hamden, Honolulu, Houston, Huntington Park, Idaho Falls, Jacksonville, Jefferson City, Johns Creek, Kansas City, Kenosha, Kissimmee, Knoxville, Lake City, Lakeland, La Mesa, Lancaster, Las Vegas, Lenoir, Lewisville, Lexington, Linden, Lombard, Long Beach, Macon, Malden, Manassas, Marietta, Mesquite, Methuen, Miami, Miami Lakes, Monroe, Mooresville, Morehead City, Morgantown, Muncie, Naples, New Port Richey, New York, Norfolk, North Las Vegas, Oak Lawn, Oklahoma City, Olney, Omaha, Orange, Orlando, Ormond Beach, Owensboro, Oxon Hill, Palm Beach Gardens, Palmetto Bay, Pembroke Pines, Philadelphia, Phoenix, Pittsburgh, Pomona, Port Charlotte, Richmond, Riverhead, Riverview, Rochester, Saint Augustine, Salisbury, Salt Lake City, San Antonio, San Bernardino, San Diego, San Marcos, Santa Rosa, Saratoga Springs, Savannah, Scottdale, Shavano Park, Sherman, Shreveport, Slidell, Smithfield, Somerset, Stamford, Stephenville, St Louis, St. Petersburg, Sun City West, Tacoma, Tempe, Thomasville, Tomball, Topeka, Torrance, Troy, Tucker, Tucson, Union, Uniontown, University Park, Vista, Waco, Wausau, Wauwatosa, Wellington, Weslaco, West Chester, Westfield, West Jordan, Westlake, West Monroe, West Seneca, Wichita, Wilmington, Winchester, Winston-Salem, Yardley, Yuma, Zachary
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
No phaseTaking people
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
Where
Birmingham
Age
16 years to 56 years
People
174
Run by
University of Alabama at Birmingham
See details and how to joinNCT07778966
Phase 4Taking people
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
Where
Albuquerque, Austin, Birmingham, Chapel Hill, Chicago, Columbus, Falls Church, Greenville, Houston, Jackson, Los Angeles, Milwaukee, New Orleans, New York, Norfolk, Pittsburgh, Providence, Salt Lake City, San Francisco
Age
14 years to 35 years
People
10,742
Run by
Ohio State University
See details and how to joinNCT06468202