Following People With Cushing's Syndrome to Track Long-Term Outcomes

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 14 or older with Cushing's syndrome, either active or treated, to follow their routine care and outcomes over time.

Age

14 years or older

Sex

All sexes can join.

Disease stage

Active or treated overt Cushing's (from a pituitary, ectopic, or adrenal tumor), mild adrenal Cushing's syndrome (MACS), or a silent corticotroph tumor. The study doctor confirms the diagnosis.

Biomarker or test result

Diagnosis is based on test results such as 24-hour urinary free cortisol, ACTH levels, midnight salivary cortisol, or dexamethasone suppression testing. Pituitary Cushing's also needs a pituitary lesion on MRI. A silent corticotroph tumor needs surgical pathology that is positive for ACTH.

Main reasons for not taking part

• Cushing's syndrome caused by medicines (iatrogenic Cushing's)

The registry criteria, word for word

What the trial wants to find out

The purpose of this study is to follow participants with Cushing's syndrome during the course of their routine care and to form a data registry to study long term participant outcomes.

The group in the trial

• Participants with Cushing's Syndrome

  Treatment: Cushing's QoL (Quality of Life Questionnaire), Nottingham Health Profile (NHP), Hospital Anxiety and Depression Scale (HADS), Perceived Stress Scale (PSS), Barratt's Impulsivity Scale (BIS), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), State Food Craving Questionnaire-State (FCQ-S), Trait Food Craving Questionnaire-Trait (FCQ-T), Visual Analogue Scale (VAS), and Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant