Cushing's syndrome trials in United States

In United States 21 Also abroad 49

21 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Long-Term Follow-Up of Survivors of Pediatric Cushing Disease
Where
Bethesda
Age
5 years to 90 years
People
240
Run by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
See details and how to joinNCT03831958
Phase 1/2Not yet taking people in United States
Relacorilant in Patients With Poorly Controlled Type 2 Diabetes and Autonomous Cortisol Secretion
Where
San Antonio
Age
18 years to 75 years
People
34
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT07925801
Phase 4Taking people
Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome
Where
Canton, Jacksonville, Weslaco
Age
18 years and over
People
63 worldwide
Run by
RECORDATI GROUP
See details and how to joinNCT07247162 · EU 2025-524649-28-00
Early phase 1Taking people
FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease
Where
Rochester
Age
18 years and over
People
50
Run by
Mayo Clinic
See details and how to joinNCT07460232
No phaseTaking people
Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
14 years and over
People
300
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT03364803
Phase 4Taking people
Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)
Where
Baltimore
Age
18 years and over
People
10
Run by
Johns Hopkins University
See details and how to joinNCT07247058
Phase 2Taking people
Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism
Where
Bethesda
Age
18 years to 120 years
People
80
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06246357
No phaseTaking people
An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
Where
Bethesda
Age
2 years to 70 years
People
2,000
Run by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
See details and how to joinNCT00001595
Phase 2Taking people
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Where
Albany, Anderson, Atlanta, Austin, Boise, Chandler, Chapel Hill, Chicago, Cincinnati, Columbus, Dallas, Edgewater, Edgewood, Eugene, Fort Lauderdale, Fountain Valley, Greenville, Houston, Huntington Park, Lafayette, La Mesa, Lampasas, Las Vegas, Lewisville, Lincoln, Long Beach, Los Angeles, Metairie, Miami, Mission, Morehead City, Mt. Pleasant, New Orleans, New Port Richey, Northridge, Omaha, Port Charlotte, Port Orange, Rockville, Round Rock, San Antonio, San Diego, Seabrook, Springfield, Suffolk, Troy, Tucson, Vienna, Weslaco, West Chester, West Des Moines, West Jordan, Wichita, Wilmington, Winter Park
Age
18 years and over
People
1,500
Run by
Sparrow Pharmaceuticals
See details and how to joinNCT07296484
Phase 2Taking people
Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome
Where
Bethesda
Age
18 years to 80 years
People
80
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT02019706
No phaseTaking people
Evaluation of Adults With Endocrine and Metabolic-Related Conditions
Where
Bethesda
Age
18 years to 100 years
People
1,250
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT02830308
Phase 2Taking people
Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS
Where
Rochester
Age
18 years and over
People
90
Run by
Mayo Clinic
See details and how to joinNCT07138274
No phaseTaking people
Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)
Where
Rochester
Age
18 years and over
People
700
Run by
Mayo Clinic
See details and how to joinNCT04543253
No phaseTaking people
A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement
Where
Ann Arbor
Age
18 years to 75 years
People
12
Run by
University of Michigan
See details and how to joinNCT06430528
Phase 2Taking people
Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome
Where
Bethesda
Age
18 years to 70 years
People
140
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT06635629
Phase 2Taking people
Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease
Where
Los Angeles
Age
18 years and over
People
20
Run by
University of California, Los Angeles
See details and how to joinNCT05971758
No phaseTaking people
DDAVP for Pituitary Adenoma
Where
Bethesda
Age
8 years to 99 years
People
22
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT04569591
Phase 2Taking people
Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome
Where
Bethesda, Cape Coral, Chicago, San Francisco, Weslaco
Age
2 years to 17 years
People
12 worldwide
Run by
RECORDATI GROUP
See details and how to joinNCT03708900 · EU 2024-516825-30-00
No phaseTaking people
IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion
Where
Dallas
Age
18 years and over
People
75
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07361874
Phase 2Taking people
Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)
Where
Rochester
Age
18 years and over
People
15
Run by
Mayo Clinic
See details and how to joinNCT07104812
No phaseTaking people
Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors
Where
Rochester
People
110
Run by
Mayo Clinic
See details and how to joinNCT07335315