Comprehensive Assessment of Neurodegeneration and Dementia
Key facts
- Where
- Calgary, Edmonton, Halifax, Hamilton, London, Montreal, Ottawa, Peterborough, Québec, Sherbrooke, Toronto, Vancouver, Victoria, and Waterloo, CanadaSee the 19 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 90 years old?
Where in Canada
- University Of CalgaryCalgary, CanadaTaking people
- University of Alberta HospitalEdmonton, CanadaTaking people
- Veteran's Memorial BuildingHalifax, CanadaTaking people
- Hamilton General HospitalHamilton, CanadaTaking people
- Gait and Brain LabLondon, CanadaTaking people
- St. Joseph's Health Care LondonLondon, CanadaTaking people
- Clinique de cognition Institut universitaire de gériatrie de MontréalMontreal, CanadaTaking people
- Jewish General Hospital/McGill Memory ClinicMontreal, CanadaTaking people
- Research Institute of the McGill University Health CentreMontreal, CanadaNo longer taking part
- Bruyère Research InstituteOttawa, CanadaNo longer taking part
- Kawartha CentrePeterborough, CanadaNo longer taking part
- Hôpital Enfant-JésusQuébec, CanadaTaking people
- Centre de recherche sur le vieillissement CIUSSS de l'Estrie-CHUSSherbrooke, CanadaNo longer taking part
- Baycrest Clinical UnitToronto, CanadaTaking people
- Sunnybrook Health Sciences CentreToronto, CanadaNo longer taking part
- University Health Network Memory ClinicToronto, CanadaNo longer taking part
- Djavad Mowafaghian Centre for Brain HealthVancouver, CanadaTaking people
- Island HealthVictoria, CanadaNot yet recruiting
- University of WaterlooWaterloo, CanadaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- McGill University
- Trial code
- NCT03402919
- Record updated
- 20 January 2026
- Original description
This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits. Participants are/will be recruited at sites across Canada and will undergo assessments, neuroimaging, and biological sample collection.Read full original descriptionShow less
The Comprehensive Assessment of Neurodegeneration and Dementia Study
This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits. Participants are/will be recruited at sites across Canada and will undergo assessments, neuroimaging, and biological sample collection.
Inclusion: Has subjective or objective cognitive impairment; Written informed consent must be obtained and documented (from the patient or, where jurisdictions allow it, from a caregiver/family member); Sufficient proficiency in English or French to undertake self report and neuropsychological testing; Geographic accessibility to the study site; Must have a study partner who can participate as required in the protocol (provide corroborative information); Up to 12 years of education; Fits into one of the following groups: Cognitively Unimpaired, Subjective Cognitive Impairment, Mild Cognitive Impairment, Vascular Mild Cognitive Impairment, Parkinson's Disease, Parkinson's Disease with Mild Cognitive Impairment.
Exclusion: The presence of other significant known chronic brain disease such as: moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, a serious developmental handicap, malignant tumors, Parkinson's disease (other than for the Parkinson's cohort), and other rarer brain illnesses; Ongoing alcohol or drug abuse which in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures; Symptomatic stroke within the previous year; Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure.