Accelerated iTBS for Post Partum Depression
Key facts
- Who runs it
- Medical University of South Carolina
- Where
- Charleston, United StatesSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 40 people, planned
- Started
- 24 Jan 2018
- Expected to end
- 30 Aug 2027
- Type of study
- Interventional
- Treatments tested
- iTBS
- Record updated
- 22 May 2026
Who can take part
- Age
- 18 years to 50 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Participants must be able to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments
- Participants must be over the age of 18
- Participants must meet criteria for post-partum depression: a) onset of symptoms in the first year postpartum
- Participants must have a HRSD17 greater than or equal to 14 at baseline
Who cannot take part
- Participants must not have any contraindications to receiving rTMS (e.g. metal implanted above the neck, history of seizure, any known brain lesion)
- Participants must not meet moderate or severe use disorder of any substance with the exception of Tobacco Use Disorder
- Participants must not have a history of dementia or other cognitive impairment
- Participants must not have any unstable general medical conditions
- Participants must not be pregnant
- Participants must not have current psychotic symptoms
- Participants must not have active suicidal ideation requiring hospitalization or a suicide attempt within the past 3 months
- Participants must not have had eclampsia during pregnancy
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Where in United States
- Medical University of South CarolinaCharleston, United StatesContact: Lisa McTeague, PhDTaking people
About the trial
What the trial wants to find out
Study 1: The investigators are studying the feasibility and tolerability of 10x/day intermittent theta burst (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over the course of 6 days for women with post-partum depression. The investigators further aim to characterize the anticipated anti-depressant effect of this treatment paradigm.
Read full original descriptionShow less
Study 2: The investigators are studying the feasibility and tolerability of 12 sessions/day of intermittent theta burse (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over 5 days for women with post-partum depression. The investigators aim to compare the two different treatment schedules.
The group in the trial
- iTBSTreatment being tested
accelerated iTBS to Left DLPFC
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- An Open Label Study to Assess the Feasibility and Tolerability of Accelerated Theta Burst Repetitive Transcranial Magnetic Stimulation (iTBS-rTMS) for the Treatment of Post-Partum Depression
- Fit questions
- Built from NCT03417960, who can take part
- Record updated
- 22 May 2026