Postpartum depression trials in United States

In United States 46 Also abroad 130

46 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Center M Randomized Trial
Where
Portland
Age
18 years and over
People
160
Run by
Oregon Health and Science University
See details and how to joinNCT07304895
No phaseEnrolling by invitation
Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial
Where
Boston
Age
18 years and over
People
428
Run by
Massachusetts General Hospital
See details and how to joinNCT07460063
No phaseTaking people
Maternal Stress on Human Milk and Infant Outcomes
Where
Coeur d'Alene
Age
18 years to 50 years
People
500
Run by
University of Idaho
See details and how to joinNCT04821544
Phase 1Taking people
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
Where
Pittsburgh, Salt Lake City
Age
18 years and over
People
50
Run by
University of Utah
See details and how to joinNCT06767566
No phaseTaking people
Restoring Emotional Needs With Exogenous Ketones for Women With Postpartum Depression
Where
Columbus
Age
18 years to 45 years
People
40
Run by
Ohio State University
See details and how to joinNCT07919392
No phaseTaking people
The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.
Where
Columbia
Age
18 years and over
People
350
Run by
University of South Carolina
See details and how to joinNCT07787845
No phaseNot yet taking people in United States
AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety
Where
Honolulu
Age
18 years and over
People
100
Run by
University of Hawaii
See details and how to joinNCT07866053
No phaseNot yet taking people in United States
Improving Perinatal Mental Health Through a Collaborative, Community Health Worker and Social Worker Intervention
Where
Austin
Age
18 years and over
People
45
Run by
American University
See details and how to joinNCT07880457
No phaseNot yet taking people in United States
Postpartum Care in the NICU Multi-Site
Where
Bryn Mawr, Doylestown, King of Prussia, Lancaster, Media, Newark, Norristown, Paoli, Penn Wynne, Philadelphia, Voorhees Township, West Chester
Age
18 years and over
People
756
Run by
Children's Hospital of Philadelphia
See details and how to joinNCT07873190
No phaseTaking people
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
Where
Chicago
Age
18 years and over
People
30
Run by
University of Illinois Chicago
See details and how to joinNCT07485036
No phaseTaking people
SAINT in Postpartum Depression (PPD)
Where
Austin, Charleston, New York, Worcester
Age
18 years to 45 years
People
192
Run by
Magnus Medical
See details and how to joinNCT07210255
No phaseTaking people
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
Where
Gainesville
Age
15 years to 49 years
People
516
Run by
University of Florida
See details and how to joinNCT07799805
No phaseTaking people
Accelerated TMS for Perinatal Depression
Where
Boston
Age
18 years to 55 years
People
24
Run by
Brigham and Women's Hospital
See details and how to joinNCT06968390
No phaseTaking people
Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders
Where
Leominster
Age
18 years and over
People
60
Run by
University of Massachusetts, Worcester
See details and how to joinNCT07458698
Phase 3Taking people
Brexanolone Lifting Outcomes Of Moms
Where
Aurora, Canoga Park, Chapel Hill, Chicago, Clinton, Decatur, Idaho Falls, Las Vegas, Manhattan, New Orleans, Orem, Plano, Princeton, Richardson, Tucson, Walnut Creek
Age
15 years to 45 years
People
120
Run by
Lipocine Inc.
See details and how to joinNCT07822321
No phaseTaking people
OBWELL: Innovative Psychotherapeutic Intervention to Treat Postpartum Depression
Where
Hackensack
Age
18 years and over
People
72
Run by
Hackensack Meridian Health
See details and how to joinNCT06991166
No phaseTaking people
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone
Where
Cambridge
Age
18 years and over
People
300
Run by
Biogen
See details and how to joinNCT07398469
No phaseTaking people
Engage & Connect: A Psychotherapy for Postpartum Depression
Where
New York
People
60
Run by
Weill Medical College of Cornell University
See details and how to joinNCT05585164
No phaseTaking people
Understanding the Role of Doulas in Supporting People With PMADs
Where
Missoula
Age
18 years and over
People
75
Run by
University of Montana
See details and how to joinNCT05763537
No phaseTaking people
Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
Where
Ann Arbor
Age
18 years and over
People
30
Run by
University of Michigan
See details and how to joinNCT07766161
No phaseTaking people
Collaborative Care Model for Perinatal Wellness Support Services - Population-Level Equity-Centered Systems Change
Where
Providence
Age
18 years and over
People
14,820
Run by
Women and Infants Hospital of Rhode Island
See details and how to joinNCT06849869
No phaseNot yet taking people in United States
Feasibility and Acceptability of a Novel Digital Intervention For Perinatal Men Who Have Depression or Anxiety
Where
Providence
Age
18 years and over
People
45
Run by
Women and Infants Hospital of Rhode Island
See details and how to joinNCT07742566
No phaseTaking people
Parents and Babies Pilot
Where
Chicago
Age
18 years and over
People
16
Run by
Northwestern University
See details and how to joinNCT07607613
No phaseTaking people
Implementation of a Clinical Decision Support Tool for Postpartum Depression
Where
Brooklyn, New York
Age
18 years and over
People
160
Run by
Weill Medical College of Cornell University
See details and how to joinNCT06818734
No phaseTaking people
Feasibility and Acceptability of a Novel Digital Intervention to Prevent Paternal Postpartum Depression
Where
Providence
Age
18 years and over
People
90
Run by
Women and Infants Hospital of Rhode Island
See details and how to joinNCT07594743