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Tests a DNA methylation signature for thyroid cancer in patients with thyroid nodules

Studies a DNA test for detecting thyroid cancer in people with thyroid nodules.

Plain-language title generated from the registry record
Registry title: Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules

Key facts

Where
Duarte, United StatesSee the site

Where in United States

  • City of Hope Medical CenterDuarte, United StatesTaking people

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Trial details

Who runs it
City of Hope Medical Center
Trial code
NCT03676647
Record updated
2 June 2026
Original description
This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.Read full original descriptionShow less

Retrospective-Prospective Collection of Thyroid Specimens After FNA

This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules. Using diagnostic testing, such as the diagnostic DNA methylation signature, may be a less invasive way to check for thyroid cancer.

Inclusion: All patients undergoing FNA for thyroid nodule diagnosis; Any race and ethnicity are eligible for the study; Patient should have thyroid nodule(s) with indeterminate diagnosis after FNA (Bethesda category of indeterminate FNA [III-V]).

ClinicalTrials.gov NCT03676647