Studies Recovery From Muscle Weakness After Severe Heart or Lung Failure
Observes patients with severe heart or lung failure to study factors affecting weakness recovery.
Plain-language title generated from the registry record
Registry title: Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
Key facts
- Where
- London, United KingdomSee the site
Where in United Kingdom
- St. Bartholomew's Hospital, Barts NHS TrustLondon, United KingdomTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Barts & The London NHS Trust
- Trial code
- NCT03753412
- Record updated
- 7 January 2026
- Original description
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.Read full original descriptionShow less
Prospective Observational Study Regarding the Determinants of Functional Disability and Quality of Life in Patients Recovering From Severe Acute Cardiac or Respiratory Failure Considered for Mechanical Cardiorespiratory Support (CLEVERER)
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.
Inclusion: Above the age of 18; Adults with severe cardio-respiratory failure requiring ECMO; Adults who have had personal and professional consultees agree to enrol them in the trial.
Exclusion: Previous Stroke; Neuromuscular disease; Malignancy; Underlying neuromuscular disease; paediatrics.