Heart failure trials in United Kingdom

In United Kingdom 95 Also abroad 1261

95 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects With Reduced Ejection Fraction
Where
Leeds, London
Age
40 years and over
People
50 worldwide
Run by
Axon Therapies, Inc.
See details and how to joinNCT07403058
No phaseTaking people
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Where
Birmingham, Blackpool, Bristol, Leeds, Leicester, Liverpool, London, Manchester, Middlesbrough, Northampton, Nottingham, Sheffield, Southampton
People
20,000 worldwide
Run by
Medtronic
See details and how to joinNCT00271180
Phase 3Taking people
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Where
Basingstoke, Cottingham, Dudley, Dundonald, Glasgow, Harefield, Southampton, Swindon
Age
18 years to 85 years
People
1,800 worldwide
Run by
Cytokinetics
See details and how to joinNCT06736574 · EU 2024-519219-32-00
No phaseTaking people
ELEVATE-HFpEF Clinical Study
Where
Leeds, London, Manchester
Age
40 years and over
People
700 worldwide
Run by
Medtronic Cardiac Rhythm and Heart Failure
See details and how to joinNCT06678841
Phase 2/3Taking people
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Where
London, Newcastle upon Tyne
Age
29 days to 17 years
People
342 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT05714085 · EU 2022-501238-52-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Airdrie, Ashington, Belfast, Bournemouth, Bridgend, Bristol, Chichester, Dundee, Exeter, Glasgow, Great Cambourne, High Wycombe, Inverness, Kilmarnock, Leicester, London, Manchester, Newcastle upon Tyne, Portadown, Craigavon, Sandbach, Stockton-on-Tees, Thetford, Wakefield, West Kirby
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Where
Barnet, Bristol, Exeter, Halifax, High Wycombe, London, Oldham, Sheffield, Truro, York
Age
18 years and over
People
6,712 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06424288 · EU 2023-509706-30-00
Phase 3Taking people
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Where
Bristol, Clydebank, Exeter, Halifax, Harrow, London
Age
18 years and over
People
4,200 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06935370 · EU 2024-519525-38-00
Phase 3Taking people
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Belfast, Bristol, Glasgow, Leeds, Leicester, Liverpool, Newcastle upon Tyne
Age
Up to 18 years
People
117 worldwide
Run by
Bayer
See details and how to joinNCT07192952 · EU 2024-519830-22-00
Phase 2Taking people
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Where
Belfast, Chichester, Dundee, High Wycombe, London, Norwich, Sheffield
Age
18 years to 79 years
People
620 worldwide
Run by
Pfizer
See details and how to joinNCT06991257 · EU 2024-518438-94-00
Phase 3Taking people
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Where
Aberdeen, Chesterfield, Dundee, Gatley, Glasgow, London, Norwich, Penzance, Redruth, Sandbach, Southampton, Swansea, Weston-super-Mare, Wolverhampton, Woodbridge, Yate
Age
40 years and over
People
11,300 worldwide
Run by
AstraZeneca
See details and how to joinNCT06677060 · EU 2024-514506-32-00
Phase 3Taking people
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Where
Bellshill, Birmingham, Cardiff, Liverpool, London, Manchester
Age
18 years and over
People
1,280 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07207811
No phaseTaking people
Arterial Stiffness and Endothelial Function in Heart Failure
Where
Coventry
Age
18 years to 90 years
People
50
Run by
Coventry University
See details and how to joinNCT07713719
No phaseNot yet taking people in United Kingdom
Right Heart Injury Monitoring on ECMO
Where
Cambridge
Age
18 years and over
People
30
Run by
Papworth Hospital NHS Foundation Trust
See details and how to joinNCT07880730
No phaseEnrolling by invitation
Global Utilization And Registry Database for Improved heArt preservatioN
Where
Manchester
People
4,000 worldwide
Run by
Paragonix Technologies
See details and how to joinNCT04141605
Phase 3Taking people
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Where
Belfast, Bristol, Glasgow, Leeds, Leicester, Liverpool, Newcastle upon Tyne
Age
6 months to 17 years
People
111 worldwide
Run by
Bayer
See details and how to joinNCT07188805 · EU 2024-519829-38-00
Phase 2Taking people
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Where
London
Age
18 years to 80 years
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07830719 · EU 2026-525974-21-00
Phase 3Taking people
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Where
Airdrie, Barnet, Cambridge, Clydebank, Exeter, Harefield, Hastings, High Wycombe, Kent, Kings Lynn, Lincoln, London, Middlesbrough, Portsmouth, Sheffield, Sunderland, Wakefield
Age
18 years to 130 years
People
3,850 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307652 · EU 2023-508162-15-00
No phaseTaking people
Prospective Evaluation of AI-ECG for SHD Detection
Where
Bristol, London
Age
18 years to 90 years
People
590
Run by
Imperial College London
See details and how to joinNCT07057466
No phaseTaking people
A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting
Where
Multiple Locations
Age
18 years and over
People
2,000 worldwide
Run by
Bayer
See details and how to joinNCT07235462
Phase 2Taking people
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Where
Birmingham, High Wycombe, London, Middlesbrough, Southampton
Age
40 years to 84 years
People
200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06979362 · EU 2024-515796-35-00
No phaseNot yet taking people in United Kingdom
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation
Where
Leicester
Age
18 years and over
People
80
Run by
University of Leicester
See details and how to joinNCT07500948
No phaseNot yet taking people in United Kingdom
Remote Monitoring and Optimization of Heart Failure Therapy
Where
Southampton
Age
18 years to 85 years
People
800 worldwide
Run by
Zoll Medical Corporation
See details and how to joinNCT07622472
No phaseEnrolling by invitation
FIND HF Risk-guided Screening for Heart Failure - Pilot Study
Where
Leeds
Age
40 years and over
People
475
Run by
University of Leeds
See details and how to joinNCT07367841
No phaseTaking people
Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation
Where
Liverpool
Age
18 years and over
People
2,600 worldwide
Run by
Insel Gruppe AG, University Hospital Bern
See details and how to joinNCT07852221